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Articles Published Processes
10/21/2020 3:38:05 PM | Browse: 602 | Download: 780
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Received |
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2020-05-10 05:20 |
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Peer-Review Started |
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2020-05-10 05:21 |
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To Make the First Decision |
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Return for Revision |
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2020-06-13 02:10 |
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Revised |
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2020-06-24 17:39 |
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Second Decision |
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2020-09-24 10:57 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-09-25 05:32 |
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Articles in Press |
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2020-09-25 05:32 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-10-20 11:40 |
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Publish the Manuscript Online |
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2020-10-21 15:38 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Real-world treatment attrition rates in advanced esophagogastric cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Erica S Tsang, Howard J Lim, Daniel J Renouf, Janine M Davies, Jonathan M Loree and Sharlene Gill |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Sharlene Gill, MD, Doctor, Medicine, BC Cancer, 600 West 10th Avenue, Vancouver V5Z 4E6, Canada. sgill@bccancer.bc.ca |
| Key Words |
Esophagogastric cancer; Gastric cancer; Treatment attrition; Systemic therapy; Treatment outcomes; Real-world evidence |
| Core Tip |
Despite the availability of later lines of therapy for esophagogastric cancer (EGC), there remains limited real-world data about the treatment attrition rates between lines of therapy. In this population-based analysis, we characterize the use and treatment attrition rates for patients with advanced EGC. Among 245 patients, there was a high level of treatment attrition, with 50% receiving one line of therapy, 34% receiving two lines, and 14% receiving three-lines. Improved survival was associated with better baseline Eastern Cooperative Oncology Group and increased lines of therapy. This real-world analysis demonstrating such steep attrition rates highlights the unmet need for more efficacious early-line treatment options. |
| Publish Date |
2020-10-21 15:38 |
| Citation |
Tsang ES, Lim HJ, Renouf DJ, Davies JM, Loree JM, Gill S. Real-world treatment attrition rates in advanced esophagogastric cancer. World J Gastroenterol 2020; 26(39): 6027-6036 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i39/6027.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i39.6027 |
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