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11/20/2020 4:04:17 AM | Browse: 19 | Download: 34
Publication Name World Journal of Gastroenterology
Manuscript ID 57209
Country/Territory Japan
2020-05-29 01:08
Peer-Review Started
2020-05-29 01:08
To Make the First Decision
Return for Revision
2020-06-12 18:28
2020-06-24 16:13
Second Decision
2020-08-26 10:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-08-27 00:38
Articles in Press
2020-08-27 00:38
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-10-16 02:13
Typeset the Manuscript
2020-11-19 01:08
Publish the Manuscript Online
2020-11-20 04:04
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biochemistry and Molecular Biology
Manuscript Type Basic Study
Article Title Tissue microarray-chip featuring computerized immunophenotypical characterization more accurately subtypes ampullary adenocarcinoma than routine histology
Manuscript Source Invited Manuscript
All Author List Matteo Palmeri, Niccola Funel, Gregorio Di Franco, Niccolò Furbetta, Desirée Gianardi, Simone Guadagni, Matteo Bianchini, Luca E Pollina, Claudio Ricci, Marco Del Chiaro, Giulio Di Candio and Luca Morelli
Author(s) ORCID Number
Matteo Palmeri http://orcid.org/0000-0002-9343-278X
Niccola Funel http://orcid.org/0000-0002-5028-2363
Gregorio Di Franco http://orcid.org/0000-0003-2156-369X
Niccolò Furbetta http://orcid.org/0000-0002-7135-2666
Desirée Gianardi http://orcid.org/0000-0002-6238-9176
Simone Guadagni http://orcid.org/0000-0001-9072-8166
Matteo Bianchini http://orcid.org/0000-0002-2403-0621
Luca E Pollina http://orcid.org/0000-0001-7163-8050
Claudio Ricci http://orcid.org/0000-0002-0110-8836
Marco Del Chiaro http://orcid.org/0000-0002-5028-236X
Giulio Di Candio http://orcid.org/0000-0002-5221-2756
Luca Morelli http://orcid.org/0000-0002-7742-9556
Funding Agency and Grant Number
Funding Agency Grant Number
ARPA Foundation (www.fondazionearpa.it)
Corresponding author Niccola Funel, BSc, PhD, Academic Research, Postdoc, Research Scientist, Division of Surgical Pathology, University-Hospital of Pisa, Via Paradisa 2, Pisa 56124, Italy. niccola.funel@gmail.com
Key Words Ampullary adenocarcinoma; Histo-molecular phenotype; Prognostic; CK7; CK20; CDX2
Core Tip Ampullary adenocarcinomas are heterogeneous tumors with different responses to specific chemotherapy regimens and prognosis, probably because they are a heterogenous group including differing ampullary growth and overlapping of histological phenotypes. Conventional histology does not allow a definitive identification of the three subgroups. We used an immunohistochemical score based on CDX2, CK7 and CK20 and identified only two sub-types, representing two groups of apparently separate neoplastic disorders with different oncological outcomes.
Publish Date 2020-11-20 04:04
Citation Palmeri M, Funel N, Di Franco G, Furbetta N, Gianardi D, Guadagni S, Bianchini M, Pollina LE, Ricci C, Del Chiaro M, Di Candio G, Morelli L. Tissue microarray-chip featuring computerized immunophenotypical characterization more accurately subtypes ampullary adenocarcinoma than routine histology. World J Gastroenterol 2020; 26(43): 6822-6836
Url https://www.wjgnet.com/1007-9327/full/v26/i43/6822.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i43.6822
Full Article (PDF) WJG-26-6822.pdf
Full Article (Word) WJG-26-6822.docx
Manuscript File 57209-Review-Webster J.docx
Answering Reviewers 57209-Answering reviewers.pdf
Audio Core Tip 57209-Audio core tip.m4a
Biostatistics Review Certificate 57209-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 57209-Conflict-of-interest statement.pdf
Copyright License Agreement 57209-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 57209-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 57209-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 57209-Language certificate.pdf
Peer-review Report 57209-Peer-review(s).pdf
Scientific Misconduct Check 57209-Bing-Yan JP-1.png
Scientific Misconduct Check 57209-Scientific misconduct check.pdf
Scientific Editor Work List 57209-Scientific editor work list.pdf