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11/18/2020 2:20:37 PM | Browse: 20 | Download: 12
Publication Name World Journal of Clinical Oncology
Manuscript ID 57332
Country/Territory United States
Received
2020-08-05 18:21
Peer-Review Started
2020-08-05 18:21
To Make the First Decision
Return for Revision
2020-09-17 16:29
Revised
2020-10-01 02:59
Second Decision
2020-10-16 11:11
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-10-19 20:21
Articles in Press
2020-10-19 20:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-11-05 11:17
Publish the Manuscript Online
2020-11-18 14:20
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Case Report
Article Title Chemotherapy rechallenge in metastatic colon cancer: A case report
Manuscript Source Unsolicited Manuscript
All Author List Tejaswini Parlapalle Reddy, Usman Khan, Ethan Alexander Burns and Maen Abdelrahim
ORCID
Author(s) ORCID Number
Tejaswini Parlapalle Reddy http://orcid.org/0000-0003-1806-1701
Usman Khan http://orcid.org/0000-0002-6050-4230
Ethan Alexander Burns http://orcid.org/0000-0002-8905-2039
Maen Abdelrahim http://orcid.org/0000-0002-6631-5035
Funding Agency and Grant Number
Corresponding author Maen Abdelrahim, BPharm, MD, PhD, Assistant Professor, Section of GI Oncology, Department of Medical Oncology, Houston Methodist Cancer Center. Cockrell Center of Advanced Therapeutics Phase I Program, Houston Methodist Research Institute and Weill Cornell Medical College, 6445 Main ST Fl 24, Houston, TX 77030, United States. mabdelrahim@houstonmethodist.org
Key Words Metastatic colorectal cancer; Rechallenge therapy; Treatment holiday; Oxaliplatin; Irinotecan; Case report
Core Tip Despite advances in therapeutic strategies, colorectal cancer (CRC) remains a deadly disease. There are limited options for patients with chemo-refractory mCRC. We present a case of a patient with heavily treated metastatic colorectal cancer (mCRC) that was responsive to oxaliplatin-based rechallenge therapy. Oxaliplatin rechallenge therapy provided this patient with a ten-month survival benefit, marked improvement in his clinical condition, performance status, and quality of life. This case highlights the importance of considering rechallenge therapy in patients with chemo-refractory mCRC. Monitoring for oxaliplatin-associated peripheral sensory neuropathy should be considered for patients who qualify for oxaliplatin rechallenge therapy.
Publish Date 2020-11-18 14:20
Citation Reddy TP, Khan U, Burns EA, Abdelrahim M. Chemotherapy rechallenge in metastatic colon cancer: A case report. World J Clin Oncol 2020; 11(11): 959-967
Url https://www.wjgnet.com/2218-4333/full/v11/i11/959.htm
DOI https://dx.doi.org/10.5306/wjco.v11.i11.959
Full Article (PDF) WJCO-11-959.pdf
Full Article (Word) WJCO-11-959.docx
Manuscript File 57332_Auto_Edited.docx
Answering Reviewers 57332-Answering reviewers.pdf
Audio Core Tip 57332-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 57332-Conflict-of-interest statement.pdf
Copyright License Agreement 57332-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 57332-Informed consent statement.pdf
Peer-review Report 57332-Peer-review(s).pdf
Scientific Misconduct Check 57332-Scientific misconduct check.pdf
Scientific Editor Work List 57332-Scientific editor work list.pdf