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9/15/2020 4:38:36 AM | Browse: 14 | Download: 36
Publication Name World Journal of Orthopedics
Manuscript ID 57579
Country/Territory Greece
Received
2020-06-18 16:30
Peer-Review Started
2020-06-18 16:31
To Make the First Decision
Return for Revision
2020-07-02 16:19
Revised
2020-07-16 12:39
Second Decision
2020-07-30 09:40
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-08-01 21:34
Articles in Press
2020-08-01 21:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-08-05 03:14
Typeset the Manuscript
2020-09-08 05:08
Publish the Manuscript Online
2020-09-15 04:38
ISSN 2218-5836 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Orthopedics
Manuscript Type Observational Study
Article Title Factors predisposing to thrombosis after major joint arthroplasty
Manuscript Source Invited Manuscript
All Author List Zoe H Dailiana, Nikolaos Stefanou, Sokratis Varitimids, Nikolaos Rigopoulos, Apostolos Dimitroulias, Theofilos Karachalios, Konstantinos N Malizos, Despoina Kyriakou and Panagoula Kollia
ORCID
Author(s) ORCID Number
Zoe H Dailiana http://orcid.org/0000-0003-3890-0832
Nikolaos Stefanou http://orcid.org/0000-0002-6784-6022
Sokratis Varitimids http://orcid.org/0000-0003-3193-9566
Nikolaos Rigopoulos http://orcid.org/0000-0003-2210-8568
Apostolos Dimitroulias http://orcid.org/0000-0001-5747-6593
Theofilos Karachalios http://orcid.org/0000-0002-9043-0535
Konstantinos N Malizos http://orcid.org/0000-0001-6594-3649
Panagoula Kollia http://orcid.org/0000-0002-0635-3996
Funding Agency and Grant Number
Funding Agency Grant Number
Hellenic Association of Orthopaedic Surgery and Traumatology EEXOT 20022007
Corresponding author Zoe H Dailiana, MD, PhD, Professor, Surgeon, Department of Orthopaedic Surgery, Faculty of Medicine, School of Health Sciences, University of Thessaly, 3 Panepistimiou Street, Biopolis, Larissa 41500, Greece. dailiana@med.uth.gr
Key Words Arthroplasty; Thrombosis; Heparin-induced thrombocytopenia; Coagulation factors; Low-molecular-weight-heparin; Fondaparinux
Core Tip This is a prospective study aiming to evaluate the impact of genetic profile of patients and pharmacologic factors (anticoagulant chemoprophylaxis with LMWH or fondaparinux) on the development of thrombosis (including heparin-induced thrombocytopenia/thrombosis [HIT/T]) after lower limb arthroplasty. Thrombosis was related to the development of anti-PF4/heparin antibodiesand was correlated significantly to factor II and V mutations.Thus, screening of coagulation profile preoperatively could minimize the risk of post-arthroplasty thrombosis. Platelet monitoring does not uncover all cases of anti-PF4/heparin antibodiesformation, while antibodymonitoring post-anticoagulant administration, is probably unnecessary. Fondaparinux can lead to the formation of anti-PF4/heparin antibodies and may cause HIT.
Publish Date 2020-09-15 04:38
Citation Dailiana ZH, Stefanou N, Varitimids S, Rigopoulos N, Dimitroulias A, Karachalios T, Malizos KN, Kyriakou D, Kollia P. Factors predisposing to thrombosis after major joint arthroplasty. World J Orthop 2020; 11(9): 400-410
Url https://www.wjgnet.com/2218-5836/full/v11/i9/400.htm
DOI https://dx.doi.org/10.5312/wjo.v11.i9.400
Full Article (PDF) WJO-11-400.pdf
Full Article (Word) WJO-11-400.docx
Manuscript File 57579-Review-Filipodia.docx
Answering Reviewers 57579-Answering reviewers.pdf
Audio Core Tip 57579-Audio core tip.m4a
Biostatistics Review Certificate 57579-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 57579-Conflict-of-interest statement.pdf
Copyright License Agreement 57579-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 57579-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 57579-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 57579-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 57579-Language certificate.pdf
Peer-review Report 57579-Peer-review(s).pdf
Scientific Misconduct Check 57579-Bing-Yan JP-1.png
Scientific Misconduct Check 57579-CrossCheck.jpg
Scientific Misconduct Check 57579-Bing-Liu JH.jpg
Scientific Misconduct Check 57579-Scientific misconduct check.pdf
Scientific Editor Work List 57579-Scientific editor work list.pdf