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11/20/2020 4:04:17 AM | Browse: 13 | Download: 15
Publication Name World Journal of Gastroenterology
Manuscript ID 57689
Country/Territory China
2020-06-19 13:49
Peer-Review Started
2020-06-19 13:50
To Make the First Decision
Return for Revision
2020-09-12 18:44
2020-09-29 18:35
Second Decision
2020-10-15 09:44
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-10-20 04:23
Articles in Press
2020-10-20 04:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-10-24 02:55
Typeset the Manuscript
2020-11-16 01:18
Publish the Manuscript Online
2020-11-20 04:04
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Role of doublecortin-like kinase 1 and leucine-rich repeat-containing G-protein-coupled receptor 5 in patients with stage II/III colorectal cancer: Cancer progression and prognosis
Manuscript Source Unsolicited Manuscript
All Author List Xue-Ling Kang, Li-Rui He, Yao-Li Chen and Shu-Bin Wang
Author(s) ORCID Number
Xue-Ling Kang http://orcid.org/0000-0002-6281-5948
Li-Rui He http://orcid.org/0000-0001-5447-6387
Yao-Li Chen http://orcid.org/0000-0002-6264-5336
Shu-Bin Wang http://orcid.org/0000-0001-6790-6745
Funding Agency and Grant Number
Funding Agency Grant Number
Sanming Project of Shenzhen SZSM201612041
Shenzhen Science and Technology Innovation Commission Project GJHZ20180420180754917 and ZDSYS20190902092855097
Postdoctoral Science Foundation of China 2018M633095
Corresponding author Shu-Bin Wang, MD, PhD, Chief Doctor, Department of Oncology, Peking University Shenzhen Hospital, Shenzhen Key Laboratory of Gastrointestinal Cancer Translational Research, China Cancer Institute of Shenzhen-Peking University-Hong Kong University of Science and Technology Medical Center, No. 1120 Lianhua Road, Futian District, Shenzhen 518036, Guangdong Province, China. shubinwang2013@163.com
Key Words Colorectal cancer; Cancer stem cells; Doublecortin-like kinase 1; Leucine-rich repeat-containing G-protein-coupled receptor 5; Cancer prognosis; Cancer progression
Core Tip The role of doublecortin-like kinase 1 (DCLK1) and leucine-rich repeat-containing G-protein-coupled receptor 5 (Lgr5) in patients with stage II/III colorectal cancer are uncertain. In this study, we found a positive correlation between the expression of DCLK1 and Lgr5, suggesting that DCLK1 and Lgr5 are involved in the malignant pathological development of colorectal cancer (CRC). High DCLK1 expression could predict the risk of recurrence and survival in CRC patients after surgery, which may be used as a potential cancer stem cells marker for the recurrence and survival of stage II/III CRC patients.
Publish Date 2020-11-20 04:04
Citation Kang XL, He LR, Chen YL, Wang SB. Role of doublecortin-like kinase 1 and leucine-rich repeat-containing G-protein-coupled receptor 5 in patients with stage II/III colorectal cancer: Cancer progression and prognosis. World J Gastroenterol 2020; 26(43): 6853-6866
Url https://www.wjgnet.com/1007-9327/full/v26/i43/6853.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i43.6853
Full Article (PDF) WJG-26-6853.pdf
Full Article (Word) WJG-26-6853.docx
Manuscript File 57689-Review-Ma JY.docx
Answering Reviewers 57689-Answering reviewers.pdf
Audio Core Tip 57689-Audio core tip.mp3
Biostatistics Review Certificate 57689-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 57689-Conflict-of-interest statement.pdf
Copyright License Agreement 57689-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 57689-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 57689-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 57689-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 57689-Language certificate.pdf
Peer-review Report 57689-Peer-review(s).pdf
Scientific Misconduct Check 57689-Scientific misconduct check.pdf
Scientific Editor Work List 57689-Scientific editor work list.pdf