Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	58317
Country	Germany

Received	2020-07-21 02:17
Peer-Review Started	2020-07-21 02:18
To Make the First Decision
Return for Revision	2020-09-24 17:17
Revised	2020-10-07 18:29
Second Decision	2020-10-27 10:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-10-27 18:39
Articles in Press	2020-10-27 18:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2020-12-04 06:50
Publish the Manuscript Online	2020-12-11 08:07

ISSN	2150-5330 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Clinical relevance of intestinal barrier dysfunction in common gastrointestinal diseases
Manuscript Source	Invited Manuscript
All Author List	Andreas Muehler, Jason R Slizgi, Hella Kohlhof, Manfred Groeppel, Evelyn Peelen and Daniel Vitt
ORCID	Author(s) ORCID Number Andreas Muehler http://orcid.org/0000-0001-5811-5976 Jason R Slizgi http://orcid.org/0000-0001-8870-3138 Hella Kohlhof http://orcid.org/0000-0001-8279-5203 Manfred Groeppel http://orcid.org/0000-0002-6105-4083 Evelyn Peelen http://orcid.org/0000-0002-9332-1801 Daniel Vitt http://orcid.org/0000-0003-4741-0317
Funding Agency and Grant Number
Corresponding Author	Andreas Muehler, MD, Research Scientist, N/A, Immunic, AG, Lochhamer Schlag 21, Gräfelfing 82166 , Germany. andreas.muehler@imux.com
Key Words	Intestinal barrier; Microbiome; Gastrointestinal disease; Inflammatory bowel disease; Inflammatory bowel syndrome; Colitis
Core Tip	Intestinal barrier dysfunction is an underlying pathophysiological feature in many gastrointestinal diseases. Understanding barrier dysfunction may help drive a deeper understanding of gastrointestinal pathology and identify novel way(s) to manage and/or treat disease. Here, we summarize the evidence supporting intestinal barrier dysfunction in common immune-mediated gastrointestinal diseases and its clinical relevance.
Publish Date	2020-12-11 08:07
Citation	Muehler A, Slizgi JR, Kohlhof H, Groeppel M, Peelen E, Vitt D. Clinical relevance of intestinal barrier dysfunction in common gastrointestinal diseases. World J Gastrointest Pathophysiol 2020; 11(6): 114-130
URL	https://www.wjgnet.com/2150-5330/full/v11/i6/114.htm
DOI	https://dx.doi.org/10.4291/wjgp.v11.i6.114

Full Article (PDF)	WJGP-11-114.pdf
Full Article (Word)	WJGP-11-114.docx
Manuscript File	58317_Auto_Edited.docx
Answering Reviewers	58317-Answering reviewers.pdf
Audio Core Tip	58317-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	58317-Conflict-of-interest statement.pdf
Copyright License Agreement	58317-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	58317-Language certificate.pdf
Peer-review Report	58317-Peer-review(s).pdf
Scientific Misconduct Check	58317-Bing-Ma YJ-1.jpg
Scientific Misconduct Check	58317-Bing-Fan JR-2.png
Scientific Misconduct Check	58317-Scientific misconduct check.pdf
Scientific Editor Work List	58317-Scientific editor work list.pdf