Publication Name	World Journal of Gastroenterology
Manuscript ID	5844
Country	Greece

Received	2013-09-28 15:27
Peer-Review Started	2013-09-29 12:20
To Make the First Decision	2013-12-26 10:54
Return for Revision	2014-01-17 10:00
Revised	2013-10-28 05:32
Second Decision	2014-04-23 08:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-04-23 10:03
Articles in Press	2014-05-23 11:10
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-04-28 16:21
Typeset the Manuscript	2014-08-07 18:31
Publish the Manuscript Online	2014-08-20 18:38

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Surgery
Manuscript Type	Topic Highlights
Article Title	Corticosteroid-free immunosuppression in liver transplantation: An evidence-based review
Manuscript Source	Invited Manuscript
All Author List	George Sgourakis and Georgia Dedemadi
Funding Agency and Grant Number
Corresponding Author	George Sgourakis, MD, PhD, FACS, 2nd Surgical Department and Surgical Oncology Unit, “Korgialenio-Benakio” Red Cross Hospital, 11 Mantzarou Street, Neo psychiko, 15451 Athens, Greece. ggsgourakis@yahoo.gr
Key Words	Meta-analysis; Evidence based; Hepatitis C virus recurrence; Liver transplantation; Steroid withdrawal; Orthotopic liver transplantation
Core Tip	Steroid replacement in orthotopic liver transplantation results in fewer cases of overall acute rejection in the corticosteroid free-immunosuppression arm. Tacrolimus monotherapy is a feasible immunosuppression regimen without steroid replacement, although further investigations are needed in view of chronic rejections. No significant differences were noted between the treatment groups in terms of patient and graft survival independently of steroid replacement. Male gender, living donors, cold ischemia times, acute rejection, and early histological recurrence are related to the development of advanced hepatitis. There is sufficient evidence advocating avoidance of the ab initio use of steroids in orthotopic liver transplantation.
Publish Date	2014-08-20 18:38
Citation	Sgourakis G, Dedemadi G. Corticosteroid-free immunosuppression in liver transplantation: An evidence-based review. World J Gastroenterol 2014; 20(31): 10703-10714
URL	http://www.wjgnet.com/1007-9327/full/v20/i31/10703.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i31.10703

Full Article (PDF)	WJG-20-10703.pdf
Full Article (Word)	WJG-20-10703.doc
Manuscript File	5844-Review.doc
Answering Reviewers	5844-Answering reviewers.pdf
Copyright License Agreement	5844-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	5844-Language certificate.pdf
Peer-review Report	5844-Peer reviews.pdf
Scientific Editor Work List	5844-Scientific editor work list.doc