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9/11/2014 8:39:00 PM | Browse: 589 | Download: 500
Publication Name World Journal of Gastroenterology
Manuscript ID 5845
Country/Territory Italy
Received
2013-09-28 15:30
Peer-Review Started
2013-09-29 13:44
To Make the First Decision
2013-10-14 21:08
Return for Revision
2013-10-16 17:07
Revised
2013-10-28 22:23
Second Decision
2013-11-13 12:03
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-11-13 15:15
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
2013-11-27 03:33
Typeset the Manuscript
2013-12-25 08:47
Publish the Manuscript Online
2014-01-20 16:41
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research and Experimental
Manuscript Type Topic Highlights
Article Title Hepatitis C virus-related mixed cryoglobulinemia: Is genetics to blame?
Manuscript Source Invited Manuscript
All Author List Laura Gragnani, Elisa Fognani, Alessia Piluso and Anna Linda Zignego
Funding Agency and Grant Number
Funding Agency Grant Number
“Associazione Italiana per la Ricerca sul Cancro” Investigator Grant 1461
‘‘Istituto Toscano Tumori’’
“Fondazione Istituto di Ricerche Virologiche Oretta Bartolomei Corsi”
“Ente Cassa di Risparmio di Firenze”
Corresponding author Anna Linda Zignego, MD, PhD, Center for Systemic Manifestations of Hepatitis Viruses, Department of Experimental and Clinical Medicine, University of Florence, Largo Brambilla 3, 50134 Florence, Italy. a.zignego@dmi.unifi.it
Keywords Hepatitis C virus; Mixed cryoglobulinemia; Genetics; Viral pathogenetic factors; Host pathogenetic factors
Core Tip Mixed cryoglobulinemia (MC) is the extrahepatic manifestation most strictly correlated with hepatitis C virus (HCV) infection; it is a benign autoimmune/ lymphoproliferative disorder that evolves to lymphoma in 5%-10% of cases. MC pathogenesis is still poorly understood. Several studies have tried to clarify the pathogenetic basis of MC and have suggested that HCV can trigger such a disorder only in the presence of still-undetermined genetic factors. Here, we attempt to clarify the relationship between HCV-related MC and the host's genetic background. The data that we report are heterogeneous and sometimes conflicting, so large, multicenter studies are clearly needed.
Publish Date 2014-01-20 16:41
Citation Gragnani L, Fognani E, Piluso A, Zignego AL. Hepatitis C virus-related mixed cryoglobulinemia: Is genetics to blame? World J Gastroenterol 2013; 19(47): 8910-8915
Url http://www.wjgnet.com/1007-9327/full/v19/i47/8910.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i47.8910
Full Article (PDF) WJG-19-8910.pdf
Manuscript File 5845-Review.doc
Answering Reviewers 5845-Answering reviewers.pdf
Copyright License Agreement 5845-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 5845-Language certificate.pdf
Peer-review Report 5845-Peer reviews.pdf
Scientific Editor Work List 5845-Scientific editor work list.doc