Publication Name	World Journal of Gastroenterology
Manuscript ID	5858
Country	Italy

Received	2013-09-28 16:38
Peer-Review Started	2013-09-29 14:05
To Make the First Decision	2013-10-14 21:08
Return for Revision	2013-10-16 17:15
Revised
Second Decision	2013-11-13 12:04
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-11-13 15:21
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-12-25 08:47
Publish the Manuscript Online	2014-01-14 20:11

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Surgery
Manuscript Type	Topic Highlights
Article Title	Liver transplantation for hepatocellular carcinoma: Role of inflammatory and immunological state on recurrence and prognosis
Manuscript Source	Invited Manuscript
All Author List	Matteo Cescon, Valentina Rosa Bertuzzo, Giorgio Ercolani, Matteo Ravaioli, Federica Odaldi and Antonio Daniele Pinna
Funding Agency and Grant Number
Corresponding Author	Matteo Cescon, MD, PhD, General Surgery and Transplant Unit, Department of Medical and Surgical Sciences, Alma Mater Studiorum-University of Bologna, Padiglione 25, Policlinico Sant'Orsola-Malpighi, Via Massarenti 9, 40138 Bologna, Italy. matteo.cescon@unibo.it
Key Words	Liver transplantation; Hepatocellular carcinoma; Inflammation; Immunosuppression; Recurrence
Core Tip	This review focuses on inflammatory markers recently emerged as indicators of tumor biological behavior and on immune state of patients submitted to liver transplantation for hepatocellular carcinoma (HCC), with a particular reference to the role of neutrophil-to-lymphocyte ratio. The impact of post-transplant immunosuppression on HCC recurrence is also analyzed according to the most relevant evidences published so far, which outline the importance of minimization of the use of calcineurin inhibitors and the protective role of inhibitors of the mammalian target of rapamycin.
Publish Date	2014-01-14 20:11
Citation	Cescon M, Bertuzzo VR, Ercolani G, Ravaioli M, Odaldi F, Pinna AD. Liver transplantation for hepatocellular carcinoma: Role of inflammatory and immunological state on recurrence and prognosis. World J Gastroenterol 2013; 19(48): 9174-9182
URL	http://www.wjgnet.com/1007-9327/full/v19/i48/9174.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i48.9174

Full Article (PDF)	WJG-19-9174.pdf
Manuscript File	5858-Review.doc
Answering Reviewers	5858-Answering reviewers.pdf
Copyright License Agreement	5858-Copyright assignment.pdf
Peer-review Report	5858-Peer reviews.pdf
Scientific Editor Work List	5858-Scientific editor work list.doc