Publication Name	World Journal of Gastroenterology
Manuscript ID	5876
Country	Switzerland

Received	2013-09-28 17:56
Peer-Review Started	2013-09-29 14:55
To Make the First Decision	2013-11-21 20:58
Return for Revision	2013-11-22 09:46
Revised	2013-12-13 14:56
Second Decision	2014-02-20 15:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-02-20 16:01
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-05-05 09:25
Publish the Manuscript Online	2014-05-18 12:31

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Immunology
Manuscript Type	Topic Highlights
Article Title	Immune responses to Helicobacter pylori infection
Manuscript Source	Invited Manuscript
All Author List	Mati Moyat and Dominique Velin
Funding Agency and Grant Number	Funding Agency Grant Number Swiss National Foundation 310030_141145 (to Velin D)
Corresponding Author	Dominique Velin, PhD, Service of Gastroenterology and Hepatology, Department of Medicine, Lausanne University Hospital, BH18-521, Rue du Bugnon 46, CH-1011 Lausanne, Switzerland. dominique.velin@chuv.ch
Key Words	Helicobacter pylori; Vaccine; Immune response; Peptic ulcer; Gastric cancer
Core Tip	Helicobacter pylori (H. pylori) infection is one of the most common infections in human beings worldwide. H. pylori actively induce tolerogenic signals and can be considered as a commensal bacteria belonging to the stomach microbiota. However, H. pylori also promote a chronic inflammation in the gastric mucosa and the direct action of virulence factors confers pro-carcinogenic activities to H. pylori. Hence, H. pylori cannot be considered as symbiotic bacteria but rather as part of the pathobiont. The development of a H. pylori vaccine will bring health benefits for individuals infected with antibiotic resistant H. pylori strains and population of underdeveloped countries.
Publish Date	2014-05-18 12:31
Citation	Moyat M, Velin D. Immune responses to Helicobacter pylori infection. World J Gastroenterol 2014; 20(19): 5583-5593
URL	http://www.wjgnet.com/1007-9327/full/v20/i19/5583.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i19.5583

Full Article (PDF)	WJG-20-5583.pdf
Full Article (Word)	WJG-20-5583.doc
Manuscript File	5876-Review.docx
Answering Reviewers	5876-Answering reviewers.pdf
Copyright License Agreement	5876-Copyright assignment.pdf
Peer-review Report	5876-Peer reviews.pdf
Scientific Editor Work List	5876-Scientific editor work list.doc