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12/30/2020 1:59:10 PM | Browse: 368 | Download: 648
Publication Name World Journal of Gastroenterology
Manuscript ID 59115
Country/Territory China
Received
2020-08-25 03:40
Peer-Review Started
2020-08-25 03:41
To Make the First Decision
Return for Revision
2020-09-12 04:27
Revised
2020-10-27 09:20
Second Decision
2020-11-10 11:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-11-12 21:37
Articles in Press
2020-11-12 21:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-12-01 08:29
Typeset the Manuscript
2020-12-30 00:51
Publish the Manuscript Online
2020-12-30 13:59
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Biochemistry & Molecular Biology
Manuscript Type Basic Study
Article Title Long non-coding ribonucleic acid W5 inhibits progression and predicts favorable prognosis in hepatocellular carcinoma
Manuscript Source Unsolicited Manuscript
All Author List Guang-Lin Lei, Hong-Xia Fan, Cheng Wang, Yan Niu, Tie-Ling Li, Ling-Xiang Yu, Zhi-Xian Hong, Jin Yan, Xi-Liang Wang, Shao-Geng Zhang, Ming-Ji Ren and Peng-Hui Yang
ORCID
Author(s) ORCID Number
Guang-Lin Lei http://orcid.org/0000-0002-2092-2251
Hong-Xia Fan http://orcid.org/0000-0001-9068-8459
Cheng Wang http://orcid.org/0000-0001-6213-7027
Yan Niu http://orcid.org/0000-0002-1536-8663
Tie-Ling Li http://orcid.org/0000-0003-0683-8659
Ling-Xiang Yu http://orcid.org/0000-0002-0727-400X
Zhi-Xian Hong http://orcid.org/0000-0002-0187-3351
Jin Yan http://orcid.org/0000-0002-3743-9477
Xi-Liang Wang http://orcid.org/0000-0002-2652-6874
Shao-Geng Zhang http://orcid.org/0000-0002-0479-7569
Ming-Ji Ren http://orcid.org/0000-0001-6259-1158
Peng-Hui Yang http://orcid.org/0000-0001-6519-5927
Funding Agency and Grant Number
Funding Agency Grant Number
the Natural Science Foundation of Beijing, China 7202194
the Natural Science Foundation of Beijing, China 7162185
Corresponding Author Peng-Hui Yang, MD, Professor, Fifth Medical Center of Chinese PLA General Hospital, /, No. 100 Xisihuan Zhong Lu, Fengtai District, Beijing 100039, China. yph3022017@163.com
Key Words Hepatocellular carcinoma; Long non-coding ribonucleic acid; Long non-coding ribonucleic acid W5
Core Tip Our results showed that the expression of long non-coding ribonucleic acids (lncRNAs) W5 was considerably reduced in hepatocellular carcinoma (HCC) tissues, which suppressed proliferation, migration and invasion of tumor cells in vitro. Our study also showed that low expression of lncRNA W5 correlated tumor progression and poor prognosis. Furthermore, manipulations of lncRNA W5 expression impacted on HCC biological behaviors. These results suggest that lncRNA W5 may serve as a tumor suppressor in the development and progression of HCC, and have a potential to be a diagnostic and therapeutic target in the clinical management of HCC.
Publish Date 2020-12-30 13:59
Citation Lei GL, Fan HX, Wang C, Niu Y, Li TL, Yu LX, Hong ZX, Yan J, Wang XL, Zhang SG, Ren MJ, Yang PH. Long non-coding ribonucleic acid W5 inhibits progression and predicts favorable prognosis in hepatocellular carcinoma. World J Gastroenterol 2021; 27(1): 55-68
URL https://www.wjgnet.com/1007-9327/full/v27/i1/55.htm
DOI https://dx.doi.org/10.3748/wjg.v27.i1.55
Full Article (PDF) WJG-27-55.pdf
Full Article (Word) WJG-27-55.docx
Manuscript File 59115_Auto_Edited-Webster J.docx
Answering Reviewers 59115-Answering reviewers.pdf
Audio Core Tip 59115-Audio core tip.mp3
Biostatistics Review Certificate 59115-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 59115-Conflict-of-interest statement.pdf
Copyright License Agreement 59115-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 59115-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 59115-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 59115-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 59115-Language certificate.pdf
Peer-review Report 59115-Peer-review(s).pdf
Scientific Misconduct Check 59115-Scientific misconduct check.pdf
Scientific Editor Work List 59115-Scientific editor work list.pdf