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Articles Published Processes
2/26/2021 5:58:37 AM | Browse: 414 | Download: 730
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Received |
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2020-09-09 02:58 |
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Peer-Review Started |
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2020-09-09 02:59 |
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To Make the First Decision |
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Return for Revision |
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2020-12-04 00:59 |
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Revised |
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2020-12-16 09:23 |
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Second Decision |
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2021-01-20 13:12 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2021-01-21 17:33 |
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Articles in Press |
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2021-01-21 17:33 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-01-27 21:05 |
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Typeset the Manuscript |
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2021-02-25 01:22 |
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Publish the Manuscript Online |
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2021-02-26 05:58 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Research & Experimental Medicine |
| Manuscript Type |
Basic Study |
| Article Title |
Fork head box M1 regulates vascular endothelial growth factor-A expression to promote the angiogenesis and tumor cell growth of gallbladder cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Rui-Tao Wang, Run-Chen Miao, Xing Zhang, Gang-Hua Yang, Yi-Ping Mu, Zi-Yun Zhang, Kai Qu and Chang Liu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Scientific and Technological Development Research Project Foundation of Shaanxi Province of China |
2020SF-069 |
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| Corresponding Author |
Chang Liu, MD, PhD, Chief Doctor, Professor, Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, No. 277 West Yanta Road, Xi’an 710061, Shaanxi Province, China. liuchangdoctor@163.com |
| Key Words |
Gallbladder neoplasms; Fork head box M1; Vascular endothelial growth factor-A; Angiogenesis; Progression; Prognosis |
| Core Tip |
Fork head box M1 (FoxM1) is considered an emerging molecular target associated with early metastasis, drug resistance, and poor patient survival in gallbladder cancer (GBC). Accumulating evidence suggests that vascular endothelial growth factor (VEGF) plays important roles in many kinds of tumors by inducing neoangiogenesis. In the present study, we found that VEGF-A overexpression was correlated with proliferation, invasion and poor prognosis. The results of Kaplan-Meier analysis showed that both FoxM1 and VEGF-A were associated with the survival of GBC. VEGF-A expression was regulated by FoxM1, which was the mechanism of FoxM1 enhancing the angiogenesis of GBC. |
| Publish Date |
2021-02-26 05:58 |
| Citation |
Wang RT, Miao RC, Zhang X, Yang GH, Mu YP, Zhang ZY, Qu K, Liu C. Fork head box M1 regulates vascular endothelial growth factor-A expression to promote the angiogenesis and tumor cell growth of gallbladder cancer. World J Gastroenterol 2021; 27(8): 692-707 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i8/692.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i8.692 |
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