| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Clinical features of multiple gastrointestinal stromal tumors: A pooling analysis combined with evidence and gap map
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Chen Li, Ke-Lu Yang, Quan Wang, Jin-Hui Tian, Yang Li, Zhi-Dong Gao, Xiao-Dong Yang, Ying-Jiang Ye and Ke-Wei Jiang |
| ORCID |
|
| Funding Agency and Grant Number |
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| Corresponding Author |
Ke-Wei Jiang, MD, PhD, Adjunct Professor, Chairman, Chief Doctor, Director, Surgeon, Surgical Oncologist, Department of Gastroenterological Surgery, Peking University People's Hospital, No.11 Xizhimen South Street, Xicheng District, Beijing 100044, China. jiangkewei@pkuph.edu.cn |
| Key Words |
Gastrointestinal stromal tumor; Multiple; Pooling analysis; Cross sectional study; Evidence and gap map; |
| Core Tip |
The study retrospectively collected 12 patients of Peking University People’s Hospital and 161 patients of literature research, which aimed to illustrate the demographic, oncological and surgical features of patients with multiple gastrointestinal stromal tumors (MGISTs). After analysis, MGISTs might have unique characteristics such as lower morbidity, female predominance, young age, multiple organs involvement, and more possibly occur in syndrome. Although overall survival was similar to single gastrointestinal stromal tumor, high rate of metastasis resulted in a poor recurrence free survival in MGISTs. Based upon evidence and gap map, gene detection and molecular biological analysis are necessary to explore the mechanism, and provide appropriate therapy. |
| Publish Date |
2020-12-19 11:55 |
| Citation |
Li C, Yang KL, Wang Q, Tian JH, Li Y, Gao ZD, Yang XD, Ye YJ, Jiang KW. Clinical features of multiple gastrointestinal stromal tumors: A pooling analysis combined with evidence and gap map. World J Gastroenterol 2020; 26(47): 7550-7567 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i47/7550.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i47.7550 |
