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9/11/2014 8:39:00 PM | Browse: 407 | Download: 529
Publication Name World Journal of Gastroenterology
Manuscript ID 5971
Country/Territory Japan
Received
2013-09-29 09:22
Peer-Review Started
2013-09-30 14:10
To Make the First Decision
2013-10-22 16:48
Return for Revision
2013-10-23 10:08
Revised
2013-11-13 21:19
Second Decision
2013-11-29 11:24
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-11-30 01:28
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-12-17 13:48
Publish the Manuscript Online
2014-01-20 16:41
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Topic Highlights
Article Title Cellular reprogramming and hepatocellular carcinoma development
Manuscript Source Invited Manuscript
All Author List Yun-Wen Zheng, Yun-Zhong Nie and Hideki Taniguchi
Funding Agency and Grant Number
Funding Agency Grant Number
Ministry of Education, Culture, Sports, Science and Technology of Japan 18591421
Ministry of Education, Culture, Sports, Science and Technology of Japan 20591531
Ministry of Education, Culture, Sports, Science and Technology of Japan 23591872
Research Center Network for Realization of Regenerative Medicine
Japan Science and Technology Agency 62890004
Corresponding author Hideki Taniguchi, MD, PhD, Department of Regenerative Medicine, Graduate School of Medicine, Yokohama City University, 3-9 Fuku-ura, Kanazawa-ku, Yokohama, Kanagawa 236-0004, Japan. rtanigu@med.yokohama-cu.ac.jp
Keywords Reprogramming; Hepatocellular carcinomas; Cancer stem cells; Transcription factor; Therapeutics
Core Tip Cellular reprogramming contributes to chemoresistance and radioresistance and cancer recurrence in hepatocellular carcinoma (HCC). Recent findings on cellular reprogramming in HCC are summarized and discussed, including stemness transcription factors, DNA methylation, miRNAs, tumor microenvironments, and signaling pathways. The novel therapeutic concept of reprogramming control therapy is also described, which may be a promising strategy for HCC therapy in the future.
Publish Date 2014-01-20 16:41
Citation Zheng YW, Nie YZ, Taniguchi H. Cellular reprogramming and hepatocellular carcinoma development. World J Gastroenterol 2013; 19(47): 8850-8860
Url http://www.wjgnet.com/1007-9327/full/v19/i47/8850.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i47.8850
Full Article (PDF) WJG-19-8850.pdf
Manuscript File 5971-Review.doc
Answering Reviewers 5971-Answering reviewers.pdf
Copyright License Agreement 5971-Copyright assignment.pdf
Peer-review Report 5971-Peer review(s).pdf
Scientific Editor Work List 5971-Scientific editor work list.doc