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3/25/2021 6:36:58 AM | Browse: 346 | Download: 565
Publication Name World Journal of Stem Cells
Manuscript ID 59909
Country China
Received
2020-10-06 12:52
Peer-Review Started
2020-10-06 12:53
To Make the First Decision
Return for Revision
2020-12-24 20:43
Revised
2021-01-08 09:50
Second Decision
2021-01-21 03:52
Accepted by Journal Editor-in-Chief
2021-01-22 01:58
Accepted by Company Editor-in-Chief
2021-02-15 18:19
Articles in Press
2021-02-15 18:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-02-26 00:41
Typeset the Manuscript
2021-03-24 06:12
Publish the Manuscript Online
2021-03-25 06:36
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Mesenchymal stromal cell-dependent immunoregulation in chemically induced acute liver failure
Manuscript Source Unsolicited Manuscript
All Author List Jia-Hang Zhou, Xuan Lu, Cui-Lin Yan, Xin-Yu Sheng and Hong-Cui Cao
ORCID
Author(s) ORCID Number
Jia-Hang Zhou http://orcid.org/0000-0003-0623-517X
Xuan Lu http://orcid.org/0000-0003-2893-6268
Cui-Lin Yan http://orcid.org/0000-0001-8415-3490
Xin-Yu Sheng http://orcid.org/0000-0002-0984-2592
Hong-Cui Cao http://orcid.org/0000-0002-6604-6867
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81971756
Stem Cell and Translational Research from National Key Research and Development Program of China 2016YFA0101001
Corresponding Author Hong-Cui Cao, MD, PhD, Professor, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. hccao@zju.edu.cn
Key Words Mesenchymal stromal cell; Immune response; Drug-induced liver injury; Acute liver failure; Dendritic cell
Core Tip Drug-induced liver injury (DILI) is a crucial cause of acute liver failure (ALF). Although mesenchymal stromal cells (MSCs) have not been applied to DILI in clinical trials, their efficacy has been proven in various animal models of chemically induced ALF. Immune system disorders play key roles in chemically induced ALF, and MSCs are able to regulate the immune system through soluble factors and cell-to-cell contact, and eventually improve liver damage. We herein discuss the immunomodulatory properties of MSCs in different animal models that mimic the pathology of DILI in humans.
Publish Date 2021-03-25 06:36
Citation Zhou JH, Lu X, Yan CL, Sheng XY, Cao HC. Mesenchymal stromal cell-dependent immunoregulation in chemically induced acute liver failure. World J Stem Cells 2021; 13(3): 208-220
URL https://www.wjgnet.com/1948-0210/full/v13/i3/208.htm
DOI https://dx.doi.org/10.4252/wjsc.v13.i3.208
Full Article (PDF) WJSC-13-208.pdf
Full Article (Word) WJSC-13-208.docx
Manuscript File 59909-Review-FilipodiaMSCL.docx
Answering Reviewers 59909-Answering reviewers.pdf
Audio Core Tip 59909-Audio core tip.WAV
Conflict-of-Interest Disclosure Form 59909-Conflict-of-interest statement.pdf
Copyright License Agreement 59909-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 59909-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 59909-Language certificate.pdf
Peer-review Report 59909-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 59909-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 59909-Scientific misconduct check.pdf
Scientific Editor Work List 59909-Scientific editor work list.pdf