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1/11/2021 1:20:09 PM | Browse: 478 | Download: 1121
Publication Name World Journal of Gastroenterology
Manuscript ID 60025
Country South Korea
Received
2020-10-12 06:56
Peer-Review Started
2020-10-12 06:56
To Make the First Decision
Return for Revision
2020-11-23 06:13
Revised
2020-12-05 09:25
Second Decision
2020-12-14 08:39
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-12-16 23:52
Articles in Press
2020-12-16 23:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-12-29 07:01
Publish the Manuscript Online
2021-01-11 13:20
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Cohort Study
Article Title Repeatedly elevated γ-glutamyltransferase levels are associated with an increased incidence of digestive cancers: A population-based cohort study
Manuscript Source Unsolicited Manuscript
All Author List Chang-Hoon Lee, Kyungdo Han, Da Hye Kim and Min-Sun Kwak
ORCID
Author(s) ORCID Number
Chang-Hoon Lee http://orcid.org/0000-0001-9960-1524
Kyungdo Han http://orcid.org/0000-0002-6096-1263
Da Hye Kim http://orcid.org/0000-0002-2241-3960
Min-Sun Kwak http://orcid.org/0000-0003-0353-6460
Funding Agency and Grant Number
Corresponding Author Min-Sun Kwak, MD, PhD, Assistant Professor, Internal Medicine, Seoul National University Hospital Gangnam Center, 39FL., Gangnam Finance Center 737, Yeoksam-Dong, Gangnam-gu, Seoul 06236, South Korea. kms39@snuh.org
Key Words Gamma-glutamyltransferase; Cancer; Digestive organ; Serial exam; Incident cancer; Biomarker
Core Tip We evaluate whether repeatedly elevated γ-glutamyltransferase (GGT) levels on four consecutive exams were associated with an increased incidence of digestive cancers using the population-based cohort data. In total, 3559109 participants were included with a median of 6.8 years of follow-up. Repeatedly elevated GGT levels on four consecutive exams were associated with an increased incidence of digestive cancers in a dose-response manner. This trend was more prominent in men than women and in those with healthy habits (no smoking, no alcohol consumption, and a low body mass index) than those with unhealthy habits.
Publish Date 2021-01-11 13:20
Citation Lee CH, Han K, Kim DH, Kwak MS. Repeatedly elevated γ-glutamyltransferase levels are associated with an increased incidence of digestive cancers: A population-based cohort study. World J Gastroenterol 2021; 27(2): 176-188
URL https://www.wjgnet.com/1007-9327/full/v27/i2/176.htm
DOI https://dx.doi.org/10.3748/wjg.v27.i2.176
Full Article (PDF) WJG-27-176.pdf
Full Article (Word) WJG-27-176.docx
STROBE Statement 60025-STROBE-Statement-revision.docx
Manuscript File 60025_Auto_Edited.docx
Answering Reviewers 60025-Answering reviewers.pdf
Audio Core Tip 60025-Audio core tip.m4a
Biostatistics Review Certificate 60025-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 60025-Conflict-of-interest statement.pdf
Copyright License Agreement 60025-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 60025-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 60025-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 60025-Language certificate.pdf
Supplementary Material 60025-Supplementary material.pdf
Peer-review Report 60025-Peer-review(s).pdf
Scientific Misconduct Check 60025-Bing-Yan JP-1.png
Scientific Misconduct Check 60025-Scientific misconduct check.pdf
Scientific Editor Work List 60025-Scientific editor work list.pdf