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1/11/2021 1:20:09 PM | Browse: 28 | Download: 90
Publication Name World Journal of Gastroenterology
Manuscript ID 60056
Country/Territory Brazil
Received
2020-10-26 10:54
Peer-Review Started
2020-10-26 10:55
To Make the First Decision
Return for Revision
2020-12-03 23:14
Revised
2020-12-17 22:04
Second Decision
2020-12-28 13:15
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-12-28 20:21
Articles in Press
2020-12-28 20:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-01-07 03:47
Publish the Manuscript Online
2021-01-11 13:20
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Observational Study
Article Title Real-world disease activity and sociodemographic, clinical and treatment characteristics of moderate-to-severe inflammatory bowel disease in Brazil
Manuscript Source Unsolicited Manuscript
All Author List Cyrla Zaltman, Rogério Serafim Parra, Ligia Yukie Sassaki, Genoile Oliveira Santana, Maria de Lourdes Abreu Ferrari, Sender J Miszputen, Heda M B S Amarante, Roberto Luiz Kaiser Junior, Cristina Flores, Wilson R Catapani, José Miguel Luz Parente, Mauro Bafutto, Odery Ramos, Carolina D Gonçalves, Isabella Miranda Guimaraes, Jose J R da Rocha, Marley R Feitosa, Omar Feres, Rogerio Saad-Hossne, Francisco Guilherme Cancela Penna, Pedro Ferrari Sales Cunha, Tarcia NF Gomes, Rodrigo Bremer Nones, Mikaell Alexandre Gouvea Faria, Mírian Perpétua Palha Dias Parente, António S Scotton, Rosana Fusaro Caratin, Juliana Senra and Júlio Maria Chebli
ORCID
Author(s) ORCID Number
Cyrla Zaltman http://orcid.org/0000-0002-5236-6501
Rogério Serafim Parra http://orcid.org/0000-0002-5566-9284
Ligia Yukie Sassaki http://orcid.org/0000-0002-7319-8906
Genoile Oliveira Santana http://orcid.org/0000-0001-5936-9791
Maria de Lourdes Abreu Ferrari http://orcid.org/0000-0002-2122-5538
Sender J Miszputen http://orcid.org/0000-0003-4487-5004
Heda M B S Amarante http://orcid.org/0000-0001-7449-1138
Roberto Luiz Kaiser Junior http://orcid.org/0000-0003-1952-1255
Cristina Flores http://orcid.org/0000-0003-1623-4525
Wilson R Catapani http://orcid.org/0000-0002-0412-2182
José Miguel Luz Parente http://orcid.org/0000-0003-4563-2784
Mauro Bafutto http://orcid.org/0000-0001-5585-3957
Odery Ramos http://orcid.org/0000-0002-9730-6860
Carolina D Gonçalves http://orcid.org/0000-0003-3663-4390
Isabella Miranda Guimaraes http://orcid.org/0000-0003-3401-6580
Jose J R da Rocha http://orcid.org/0000-0001-7118-0545
Marley R Feitosa http://orcid.org/0000-0002-4440-2023
Omar Feres http://orcid.org/0000-0003-3593-0526
Rogerio Saad-Hossne http://orcid.org/0000-0002-8166-0304
Francisco Guilherme Cancela Penna http://orcid.org/0000-0002-2338-5367
Pedro Ferrari Sales Cunha http://orcid.org/0000-0003-4384-2606
Tarcia NF Gomes http://orcid.org/0000-0003-2897-0327
Rodrigo Bremer Nones http://orcid.org/0000-0002-6256-2629
Mikaell Alexandre Gouvea Faria http://orcid.org/0000-0003-4121-0306
Mírian Perpétua Palha Dias Parente http://orcid.org/0000-0002-0176-717X
António S Scotton http://orcid.org/0000-0001-9247-0904
Rosana Fusaro Caratin http://orcid.org/0000-0003-0922-8530
Juliana Senra http://orcid.org/0000-0001-6787-806X
Júlio Maria Chebli http://orcid.org/0000-0003-1527-0663
Funding Agency and Grant Number
Funding Agency Grant Number
Takeda Pharmaceuticals Brazil
Corresponding Author Cyrla Zaltman, MD, PhD, Associate Professor, Internal Medicine, Rio de Janeiro Federal University, Rua Rodolpho Paulo Rocco, 255-4o Andar-Cidade Universitária-Ilha do Fundão, Rio de Janeiro 21941-913, Brazil. c.zaltman@gmail.com
Key Words Inflammatory Bowel Disease; Crohn's Disease; Ulcerative Colitis; Disease activity; Epidemiology; Treatment
Core Tip In this multicenter study from Brazil, a substantial proportion (45%, and less pronounced in the South) of Crohn’s disease patients had active disease despite being treated with biologics and immunosuppressors. One-quarter (higher in the Northeast/Midwest region) of ulcerative colitis patients had active disease, with the majority treated with 5-Aminosalicylic acid derivatives. In the largest Latin American country, regional differences were observed regarding inflammatory bowel diseases (IBD) activity and treatment patterns. Findings from this study can further elucidate about variations in clinical practice, ultimately promoting debate among specialists regarding the optimal management of IBD patients.
Publish Date 2021-01-11 13:20
Citation Zaltman C, Parra RS, Sassaki LY, Santana GO, Ferrari MLA, Miszputen SJ, Amarante HMBS, Kaiser Junior RL, Flores C, Catapani WR, Parente JML, Bafutto M, Ramos O, Gonçalves CD, Guimaraes IM, da Rocha JJR, Feitosa MR, Feres O, Saad-Hossne R, Penna FGC, Cunha PFS, Gomes TNF, Nones RB, Faria MAG, Parente MPPD, Scotton AS, Caratin RF, Senra J, Chebli JM. Real-world disease activity and sociodemographic, clinical and treatment characteristics of moderate-to-severe inflammatory bowel disease in Brazil. World J Gastroenterol 2021; 27(2): 208-223
Url https://www.wjgnet.com/1007-9327/full/v27/i2/208.htm
DOI https://dx.doi.org/10.3748/wjg.v27.i2.208
Full Article (PDF) WJG-27-208.pdf
Full Article (Word) WJG-27-208.docx
Manuscript File 60056_Auto_Edited.docx
Answering Reviewers 60056-Answering reviewers.pdf
Audio Core Tip 60056-Audio core tip.mp3
Biostatistics Review Certificate 60056-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 60056-Conflict-of-interest statement.pdf
Copyright License Agreement 60056-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 60056-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 60056-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 60056-Language certificate.pdf
Peer-review Report 60056-Peer-review(s).pdf
Scientific Misconduct Check 60056-Bing-Ma YJ-1.jpg
Scientific Misconduct Check 60056-Bing-Fan JR-2.png
Scientific Misconduct Check 60056-Scientific misconduct check.pdf
Scientific Editor Work List 60056-Scientific editor work list.pdf