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12/25/2020 10:20:16 AM | Browse: 626 | Download: 1626
Publication Name World Journal of Gastroenterology
Manuscript ID 60125
Country China
Received
2020-10-16 08:28
Peer-Review Started
2020-10-16 08:29
To Make the First Decision
Return for Revision
2020-11-03 14:00
Revised
2020-11-15 12:22
Second Decision
2020-11-30 09:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-12-06 01:47
Articles in Press
2020-12-06 01:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-12-11 22:25
Typeset the Manuscript
2020-12-21 01:39
Publish the Manuscript Online
2020-12-25 10:20
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Microbiology
Manuscript Type Observational Study
Article Title Oral microbiome and pancreatic cancer
Manuscript Source Unsolicited Manuscript
All Author List Ai-Lin Wei, Mao Li, Guo-Qing Li, Xuan Wang, Wei-Ming Hu, Zhen-Lu Li, Jue Yuan, Hong-Ying Liu, Li-Li Zhou, Ka Li, Ang Li and Mei Rosemary Fu
ORCID
Author(s) ORCID Number
Ai-Lin Wei http://orcid.org/0000-0001-5162-9499
Mao Li http://orcid.org/0000-0003-1728-9026
Guo-Qing Li http://orcid.org/0000-0003-3022-5510
Xuan Wang http://orcid.org/0000-0003-2412-3091
Wei-Ming Hu http://orcid.org/0000-0003-1605-5084
Zhen-Lu Li http://orcid.org/0000-0001-9909-5457
Jue Yuan http://orcid.org/0000-0002-8591-4738
Hong-Ying Liu http://orcid.org/0000-0001-6482-1439
Li-Li Zhou http://orcid.org/0000-0001-7084-4610
Ka Li http://orcid.org/0000-0003-1091-1505
Ang Li http://orcid.org/0000-0002-5261-7577
Mei Rosemary Fu http://orcid.org/0000-0003-3891-0109
Funding Agency and Grant Number
Funding Agency Grant Number
Expert Funding of National Natural Science Foundation of China No. 81773174
1·3·5 project for disciplines of excellence- Clinical Research Incubation and Innovation Project , West China Hospital, Sichuan University No. ZYJC18044
Clinical Research Incubation and Innovation Project of West China Hospital No. 2019HXFH009
Science and technology project of Sichuan Province No. 2020YFS0264
Corresponding Author Ang Li, MD, Professor, Department of Pancreatic Surgery, West China Hospital, Sichuan University, NO. 37 Guoxue Alley, Chengdu 610000, Sichuan Province, China. angli@scu.edu.cn
Key Words Oral microbiota; Dysbiosis; Pancreatic cancer; Cancer detection; 16s rRNA; High-throughput sequencing
Core Tip Pancreatic adenocarcinoma (PDAC) patients benefit from early detection. This study analyzed the composition and diversity of saliva microbiota in PDAC patients through 16S rRNA sequencing. Normalized z-score of bacteria abundance associated clinical data were analyzed for PDAC risk prediction. Microbiome abundance differences were found between PDAC patients with symptoms and patients without symptoms. Combined symptom and microbiome evaluation may help in early detection and risk prediction of pancreatic cancer.
Publish Date 2020-12-25 10:20
Citation Wei AL, Li M, Li GQ, Wang X, Hu WM, Li ZL, Yuan J, Liu HY, Zhou LL, Li K, Li A, Fu MR. Oral microbiome and Pancreatic Cancer. World J Gastroenterol 2020; 26(48): 7679-7692
URL https://www.wjgnet.com/1007-9327/full/v26/i48/7679.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i48.7679
Full Article (PDF) WJG-26-7679.pdf
Full Article (Word) WJG-26-7679.docx
Manuscript File 60125-Review-FilipodiaCL.docx
Answering Reviewers 60125-Answering reviewers.pdf
Audio Core Tip 60125-Audio core tip.m4a
Biostatistics Review Certificate 60125-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 60125-Conflict-of-interest statement.pdf
Copyright License Agreement 60125-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 60125-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 60125-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 60125-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 60125-Language certificate.pdf
Peer-review Report 60125-Peer-review(s).pdf
Scientific Misconduct Check 60125-Bing-Yan JP-1.png
Scientific Misconduct Check 60125-Bing-Fan JR-2.png
Scientific Misconduct Check 60125-Scientific misconduct check.pdf
Scientific Editor Work List 60125-Scientific editor work list.pdf