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Articles Published Processes
1/21/2021 1:39:43 PM | Browse: 479 | Download: 1057
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Received |
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2020-10-26 13:48 |
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Peer-Review Started |
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2020-10-26 13:49 |
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To Make the First Decision |
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Return for Revision |
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2020-11-22 00:58 |
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Revised |
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2020-11-30 21:39 |
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Second Decision |
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2020-12-08 12:33 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-12-08 19:16 |
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Articles in Press |
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2020-12-08 19:16 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-12-17 08:26 |
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Typeset the Manuscript |
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2021-01-17 06:59 |
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Publish the Manuscript Online |
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2021-01-21 13:39 |
| ISSN |
2150-5330 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Basic Study |
| Article Title |
Influence of anastomoses on intestine ischemia and cefuroxime concentrations: evaluated in ileum and colon in a porcine model
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Pelle Hanberg, Mats Bue, Maja Thomassen, Uffe Schou Løve, Josephine Olsen Kipp, Christina Harlev, Elisabeth Petersen, Kjeld Søballe and Maiken Stilling |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Pelle Hanberg, MD, N/A, Department of Orthopaedic Surgery, Horsens Regional Hospital, Sundvej 30, Horsens 8700, Denmark. pellehanberg@clin.au.dk |
| Key Words |
Anastomosis; Cefuroxime; Colon; Ileum; Ischemic metabolites; Microdialysis |
| Core Tip |
We found that only colon anastomosis was locally vulnerable to ischemia but reached similar cefuroxime concentrations as the remaining investigated intestine compartments. Our study suggests that administering 1.5 g cefuroxime 10 min prior to intestine surgery is sufficient, and that effective concentrations are sustained for approximately 2 h. This is the first study to investigate the influence of anastomoses on ileum and colon ischemic metabolites and cefuroxime concentrations in a simultaneous paired design. |
| Publish Date |
2021-01-21 13:39 |
| Citation |
Hanberg P, Bue M, Thomassen M, Løve US, Kipp JO, Harlev C, Petersen E, Søballe K, Stilling M. Influence of anastomoses on intestine ischemia and cefuroxime concentrations: evaluated in ileum and colon in a porcine model. World J Gastrointest Pathophysiol 2021; 12(1): 1-13 |
| URL |
https://www.wjgnet.com/2150-5330 /full/v12/i1/1.htm |
| DOI |
https://dx.doi.org/10.4291/wjgp.v12.i1.1 |
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