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Articles Published Processes
4/29/2021 8:35:47 AM | Browse: 324 | Download: 643
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Received |
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2020-11-17 00:01 |
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Peer-Review Started |
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2020-11-17 00:02 |
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To Make the First Decision |
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Return for Revision |
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2020-12-28 02:41 |
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Revised |
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2020-12-31 15:51 |
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Second Decision |
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2021-01-25 08:54 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2021-01-26 04:05 |
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Articles in Press |
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2021-01-26 04:05 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-02-02 01:20 |
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Typeset the Manuscript |
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2021-04-12 10:41 |
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Publish the Manuscript Online |
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2021-04-29 08:35 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Critical Care Medicine |
| Manuscript Type |
Case Report |
| Article Title |
Almitrine for COVID-19 critically ill patients – a vascular therapy for a pulmonary vascular disease: Three case reports
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Pierre Huette, Osama Abou Arab, Vincent Jounieaux, Mathieu Guilbart, Mohamed Belhout, Guillaume Haye, Hervé Dupont, Christophe Beyls and Yazine Mahjoub |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Pierre Huette, MD, Doctor, Department of Anaesthesia and Critical Care, Amiens Hospital University, Avenue Rene-Laennec, Amiens 80000, France. huette.pierre@chu-amiens.fr |
| Key Words |
COVID-19; Treatment; Acute vascular distress syndrome; Almitrine; Intensive care unit; Safety; Case report |
| Core Tip |
It has been hypothesized that increased pulmonary blood flow associated with impaired hypoxic vasoconstriction may lead to significant intrapulmonary shunt that plays a major role in Coronavirus disease 2019 (COVID-19) related severe hypoxia. In this report, three patients with refractory hypoxemia were treated with continuous infusion of almitrine, a specific pulmonary vasoconstrictor. Almitrine infusion enhanced oxygenation of patients with severe COVID-19 related acute respiratory distress syndrome without any change in pulmonary artery pressures and right ventricular function. |
| Publish Date |
2021-04-29 08:35 |
| Citation |
Huette P, Abou Arab O, Jounieaux V, Guilbart M, Belhout M, Haye G, Dupont H, Beyls C, Mahjoub Y. Almitrine for COVID-19 critically ill patients – a vascular therapy for a pulmonary vascular disease: Three case reports. World J Clin Cases 2021; 9(14): 3385-3393 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i14/3385.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i14.3385 |
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