| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Anesthesiology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Perioperative blood transfusion decreases long-term survival in pediatric living donor liver transplantation
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Karina Gordon, Estela Regina Ramos Figueira, Joel Avancini Rocha-Filho, Luiz Antonio Mondadori, Eduardo Henrique Giroud Joaquim, Joao Seda‐Neto, Eduardo Antunes da Fonseca, Renata Pereira Sustovitch Pugliese, Agustin Moscoso Vintimilla, Jose Otavio Costa Auler Jr, Maria Jose Carvalho Carmona and Luiz Augusto Carneiro D'Alburquerque |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Karina Gordon, MD, PhD, Academic Research, Attending Doctor, Staff Physician, Division of Anesthesiology, Hospital das Clínicas, University of São Paulo School of Medicine, Av. Dr. Eneas de Carvalho Aguiar, 155 8th Floor, São Paulo 05403-000, Brazil. gordonkarina00@gmail.com |
| Key Words |
Liver transplantation; Child; Blood transfusion; Outcome; Liver cirrhosis; Mortality |
| Core Tip |
This study aimed to assess whether perioperative transfusion is associated with early and late postoperative complications and mortality in small patients undergoing pediatric living donor liver transplantation (PLDLT). The volume of perioperative packed red blood cell (RBC) transfusion was the only independent risk factor for major postoperative complications. The perioperative volume of RBC > 27.5 mL/kg was an independent risk factor for mortality, increasing the risk by 3.031-fold, and was directly related to reduced patient and graft survival. In conclusion, not even massive transfusion, in the perioperative period, was associated with a significant increase in short- and long-term postoperative morbimortality after PLDLT. |
| Publish Date |
2021-03-25 11:42 |
| Citation |
Gordon K, Figueira ERR, Rocha-Filho JA, Mondadori LA, Joaquim EHG, Seda-Neto J, da Fonseca EA, Pugliese RPS, Vintimilla AM, Auler Jr JOC, Carmona MJC, D'Alburquerque LAC. Perioperative blood transfusion decreases long-term survival in pediatric living donor liver transplantation. World J Gastroenterol 2021; 27(12): 1161-1181 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i12/1161.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i12.1161 |
