Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	61638
Country	India

Received	2020-12-14 13:17
Peer-Review Started	2020-12-14 13:18
To Make the First Decision
Return for Revision	2021-02-14 06:07
Revised	2021-03-01 08:23
Second Decision	2021-04-06 11:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-04-21 04:02
Articles in Press	2021-04-21 04:02
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-05-13 06:59
Publish the Manuscript Online	2021-05-14 10:27

ISSN	2150-5330 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Neuroimmunomodulation by gut bacteria: Focus on inflammatory bowel diseases
Manuscript Source	Invited Manuscript
All Author List	Surbhi Aggarwal, Raju Ranjha and Jaishree Paul
ORCID	Author(s) ORCID Number Surbhi Aggarwal http://orcid.org/0000-0002-5741-7494 Raju Ranjha http://orcid.org/0000-0002-9389-4626 Jaishree Paul http://orcid.org/0000-0001-6700-993X
Funding Agency and Grant Number
Corresponding Author	Surbhi Aggarwal, PhD, Postdoctoral Fellow, Research Associate, Department of biochemical engineering and biotechnology, Indian Institute of Technology, Hauz Khas, Delhi 110016, India. aggarwalsurbhi28@gmail.com
Key Words	Inflammation; Gut microbiota; Inflammatory bowel disease; Enteric nervous system; Neuroimmunomodulation; Neuromediator
Core Tip	Dysbiosis in gut bacteria is a well-established factor, and the abnormality in the enteric nervous system is an emerging aspect that influences the gut inflammation. Both of them contribute to inflammatory bowel disease (IBD) pathogenesis by modulating the host immune response. Through this review, we linked the two pathological mechanisms and explained how neuroimmunomodulation by gut bacteria play a crucial role in IBD. We elaborated all the known neuromediators produced by gut bacteria and the role of each neuromediator as well as the respective gut bacteria in inflammatory signaling pathways especially in IBD
Publish Date	2021-05-14 10:27
Citation	Aggarwal S, Ranjha R, Paul J. Neuroimmunomodulation by gut bacteria: Focus on inflammatory bowel diseases. World J Gastrointest Pathophysiol 2021; 12(3): 25-39
URL	https://www.wjgnet.com/2150-5330/full/v12/i3/25.htm
DOI	https://dx.doi.org/10.4291/wjgp.v12.i3.25

Full Article (PDF)	WJGP-12-25.pdf
Full Article (Word)	WJGP-12-25.docx
Manuscript File	61638_Auto_Edited_LM.docx
Answering Reviewers	61638-Answering reviewers.pdf
Audio Core Tip	61638-Audio core tip.aac
Conflict-of-Interest Disclosure Form	61638-Conflict-of-interest statement.pdf
Copyright License Agreement	61638-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	61638-Language certificate.pdf
Peer-review Report	61638-Peer-review(s).pdf
Scientific Misconduct Check	61638-Bing-Yan JP-1.jpg
Scientific Misconduct Check	61638-Bing-Fan JR-2.png
Scientific Misconduct Check	61638-Scientific misconduct check.pdf
Scientific Editor Work List	61638-Scientific editor work list.pdf