Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	62289
Country	Canada

Received	2021-01-04 20:21
Peer-Review Started	2021-01-04 20:22
To Make the First Decision
Return for Revision	2021-01-25 05:35
Revised	2021-01-26 20:11
Second Decision	2021-03-22 06:17
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-03-22 17:12
Articles in Press	2021-03-22 17:12
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-04-06 15:09
Publish the Manuscript Online	2021-04-09 08:11

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Pathology
Manuscript Type	Minireviews
Article Title	Primary malignant vascular tumors of the liver in children: Angiosarcoma and epithelioid hemangioendothelioma
Manuscript Source	Invited Manuscript
All Author List	Sami Bannoura and Juan Putra
ORCID	Author(s) ORCID Number Sami Bannoura http://orcid.org/0000-0001-9656-2961 Juan Putra http://orcid.org/0000-0002-3487-4641
Funding Agency and Grant Number
Corresponding Author	Juan Putra, MD, Assistant Professor, Staff Physician, Department of Paediatric Laboratory Medicine, Hospital for Sick Children, 555 University Ave , Toronto M5G1X8, Ontario, Canada. juan.putra@sickkids.ca
Key Words	Pediatric; Hepatic angiosarcoma; Epithelioid hemangioendothelioma; Infantile hemangioma; Liver tumor; Molecular genetics
Core Tip	Malignant hepatic vascular neoplasms are rarely encountered in the pediatric population. This review highlights the clinicopathologic characteristics of pediatric hepatic angiosarcoma and epithelioid hemangioendothelioma. They have variable clinical and radiological findings; therefore, histologic examination is the gold standard for diagnosis. Hepatic angiosarcoma in children is characterized by whorls of spindled cells and eosinophilic globules histologically. Meanwhile, epithelioid hemangioendothelioma shows epithelioid cells with intracytoplasmic lumina and a fibromyxoid background. Diagnostic challenges and molecular alterations of these entities are discussed in the article.
Publish Date	2021-04-09 08:11
Citation	Bannoura S, Putra J. Primary Malignant Vascular Tumors of the Liver in Children: Angiosarcoma and Epithelioid Hemangioendothelioma. World J Gastrointest Oncol 2021; 13(4): 223-230
URL	https://www.wjgnet.com/1948-5204/full/v13/i4/223.htm
DOI	https://dx.doi.org/10.4251/wjgo.v13.i4.223

Full Article (PDF)	WJGO-13-223.pdf
Full Article (Word)	WJGO-13-223.docx
Manuscript File	62289_Auto_Edited_LM.docx
Answering Reviewers	62289-Answering reviewers.pdf
Audio Core Tip	62289-Audio core tip.mp4
Conflict-of-Interest Disclosure Form	62289-Conflict-of-interest statement.pdf
Copyright License Agreement	62289-Copyright license agreement.pdf
Peer-review Report	62289-Peer-review(s).pdf
Scientific Misconduct Check	62289-Scientific misconduct check.pdf
Scientific Editor Work List	62289-Scientific editor work list.pdf