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4/9/2021 5:27:04 AM | Browse: 380 | Download: 296
Publication Name World Journal of Diabetes
Manuscript ID 62628
Country/Territory Romania
Received
2021-01-13 19:35
Peer-Review Started
2021-01-13 19:35
To Make the First Decision
Return for Revision
2021-02-12 06:04
Revised
2021-02-23 22:26
Second Decision
2021-03-23 09:04
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-03-24 07:53
Articles in Press
2021-03-24 07:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-03-29 23:53
Publish the Manuscript Online
2021-04-09 05:27
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Ophthalmology
Manuscript Type Minireviews
Article Title Malfunction of outer retinal barrier and choroid in the occurrence and progression of diabetic macular edema
Manuscript Source Invited Manuscript
All Author List Ştefan Ţălu and Simona Delia Nicoara
ORCID
Author(s) ORCID Number
Ştefan Ţălu http://orcid.org/0000-0003-1311-7657
Simona Delia Nicoara http://orcid.org/0000-0002-7886-2044
Funding Agency and Grant Number
Corresponding Author Simona Delia Nicoara, MD, PhD, Chief Doctor, Full Professor, Department of Ophthalmology, Iuliu Haţieganu University of Medicine and Pharmacy, 8 Victor Babes St, Cluj-Napoca 400441, Romania. simonanicoara1@gmail.com
Key Words Diabetic macular edema; External limiting membrane; Hyperreflective foci; Inner segment/outer segment line; Optical coherence tomography; Outer retinal barrier
Core Tip Progress in optical coherence tomography technology allowed the identification of new pathogenic pathways in diabetic macular edema (DME) involving the outer retina and underlying choroid. The presence of fluid in the subretinal space is suggestive for the alteration of the outer blood retinal barrier and responds better to intravitreal triamcinolone as compared to anti- vascular endothelial growth factor. The disruption of external limiting membrane (ELM) is associated with visual impairment being a predictor of poor outcomes following the treatment with triamcinolone. The integrity of ELM and of the inner segment/outer segment line was found to correlate positively with best corrected visual acuity in DME.
Publish Date 2021-04-09 05:27
Citation Ţălu Ş, Nicoara SD. Malfunction of outer retinal barrier and choroid in the occurrence and progression of diabetic macular edema. World J Diabetes 2021; 12(4): 437-452
URL https://www.wjgnet.com/1948-9358/full/v12/i4/437.htm
DOI https://dx.doi.org/10.4239/wjd.v12.i4.437
Full Article (PDF) WJD-12-437.pdf
Full Article (Word) WJD-12-437.docx
Manuscript File 62628_Auto_Edited.docx
Answering Reviewers 62628-Answering reviewers.pdf
Audio Core Tip 62628-Audio core tip.wav
Conflict-of-Interest Disclosure Form 62628-Conflict-of-interest statement.pdf
Copyright License Agreement 62628-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 62628-Language certificate.pdf
Peer-review Report 62628-Peer-review(s).pdf
Scientific Misconduct Check 62628-Scientific misconduct check.pdf
Scientific Editor Work List 62628-Scientific editor work list.pdf