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10/13/2021 12:57:54 PM | Browse: 20 | Download: 33
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 63349
Country/Territory China
2021-03-11 12:09
Peer-Review Started
2021-02-23 09:52
To Make the First Decision
Return for Revision
2021-04-19 02:49
2021-04-22 13:47
Second Decision
2021-07-21 03:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-07-21 08:43
Articles in Press
2021-07-21 08:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-08-25 08:14
Typeset the Manuscript
2021-10-09 03:34
Publish the Manuscript Online
2021-10-13 12:57
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Basic Study
Article Title Combination of neutrophil gelatinase-associated lipocalin and matrix metalloproteinase-9 are biomarkers for the detection of tubular adenocarcinoma of colon
Manuscript Source Unsolicited Manuscript
All Author List Jun-Hua Yuan, Li-Shuang Xie, Yu-Hua Zhu, Xiao-Hua Wang, Yi-Jing Zhang and Xiao-Jun Wang
Author(s) ORCID Number
Jun-Hua Yuan http://orcid.org/0000-0002-5219-2900
Li-Shuang Xie http://orcid.org/0000-0003-3614-3209
Yu-Hua Zhu http://orcid.org/0000-0003-2179-8923
Xiao-Hua Wang http://orcid.org/0000-0002-8530-1210
Yi-Jing Zhang http://orcid.org/0000-0003-2267-608X
Xiao-Jun Wang http://orcid.org/0000-0002-5439-782X
Funding Agency and Grant Number
Funding Agency Grant Number
Shandong Key Research and Development Plan 2016GSF201020
Corresponding Author Jun-Hua Yuan, MD, Chief Physician, Department of Geriatric Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No. 324 Jingwu Weiqi Road, Huaiyin District, Jinan 250021, Shandong Province, China. yjh717299@126.com
Key Words Tubular adenocarcinoma; Colon; Neutrophil gelatinase-associated lipocalin; Matrix metalloproteinase-9; Biomarker
Core Tip Neutrophil gelatinase-associated lipocalin (NGAL) is a secreted protein, which modulates the expression of matrix metalloproteinase-9 (MMP-9) and appears in various cancers. However, it has not been explored whether NGAL or MMP-9 could be used as biomarkers in diagnosis of tubular adenocarcinoma of colon. In the present study, we demonstrated that both NGAL and MMP-9 could be used as biomarkers for diagnosis of tubular adenocarcinoma of the colon. By employing them together, the diagnosis accuracy can be further improved.
Publish Date 2021-10-13 12:57
Citation Yuan JH, Xie LS, Zhu YH, Wang XH, Zhang YJ, Wang XJ. Combination of neutrophil gelatinase-associated lipocalin and matrix metalloproteinase-9 are biomarkers for the detection of colon tubular adenocarcinoma. World J Gastrointest Oncol 2021; 13(10): 1506-1517
URL https://www.wjgnet.com/1948-5204/full/v13/i10/1506.htm
DOI https://dx.doi.org/10.4251/wjgo.v13.i10.1506
Full Article (PDF) WJGO-13-1506.pdf
Full Article (Word) WJGO-13-1506.docx
Manuscript File 63349_Auto_Edited-JPY-Webster J-Clear.docx
Answering Reviewers 63349-Answering reviewers.pdf
Audio Core Tip 63349-Audio core tip.mp3
Biostatistics Review Certificate 63349-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 63349-Conflict-of-interest statement.pdf
Copyright License Agreement 63349-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 63349-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 63349-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 63349-Language certificate.pdf
Peer-review Report 63349-Peer-review(s).pdf
Scientific Misconduct Check 63349-CrossCheck.png
Scientific Misconduct Check 63349-Bing-Gong ZM-2.png
Scientific Misconduct Check 63349-Scientific misconduct check.pdf
Scientific Editor Work List 63349-Scientific editor work list.pdf