Publication Name	World Journal of Diabetes
Manuscript ID	6381
Country	United States

Received	2013-10-15 15:43
Peer-Review Started	2013-10-16 14:41
To Make the First Decision	2013-11-12 14:29
Return for Revision	2013-11-13 15:05
Revised	2013-12-02 22:42
Second Decision	2013-12-13 13:31
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-12-13 14:18
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-02-15 16:55
Publish the Manuscript Online	2014-02-19 15:19

ISSN	1948-9358 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Endocrinology & Metabolism
Manuscript Type	Review
Article Title	Cardiac autonomic neuropathy in patients with diabetes mellitus
Manuscript Source	Invited Manuscript
All Author List	Gerasimos Dimitropoulos, Abd A Tahrani and Martin J Stevens
Funding Agency and Grant Number
Corresponding Author	Dr. Abd A Tahrani, Centre of Endocrinology, Diabetes and Metabolism, School of Clinical and Experimental Medicine, University of Birmingham, Edgbaston, B15 2TT Birmingham, United Kingdom. a.a.tahrani@bham.ac.uk
Key Words	Diabetes mellitus; Cardiac; Cardiovascular; Autonomic; Neuropathy; Dysfunction; Cardiac autonomic neuropathy; Sympathetic; Parasympathetic; Heart rate variability; Spectral analysis; Diabetic cardiomyopathy; Postural hypotension
Core Tip	Cardiac autonomic neuropathy (CAN) is a complication of diabetes mellitus that is often underdiagnosed but can lead to severe morbidity and mortality, due to the associated cardiovascular burden. New evidence has emerged surrounding its complex pathways, but its full pathogenesis is yet to be understood. CAN manifests in a spectrum of subclinical and clinical presentations, ranging from resting tachycardia to cardiomyopathy. Heart rate variability and scintigraphy have enabled the diagnosis at a subclinical stage, thus providing the opportunity for better prevention and treatment. However, no definite therapeutic approaches have been adopted to date, emphasizing the need for newer targeted treatments.
Publish Date	2014-02-19 15:19
Citation	Dimitropoulos G, Tahrani AA, Stevens MJ. Cardiac autonomic neuropathy in patients with diabetes mellitus. World J Diabetes 2014; 5(1): 17-39 Available from: URL: http://www. wjgnet.com/1948-9358/full/v5/i1/17.htm DOI: http://dx.doi. org/10.4239/wjd.v5.i1.17
URL	http://www.wjgnet.com/1948-9358/full/v5/i1/17.htm
DOI	http://dx.doi.org/10.4239/wjd.v5.i1.17

Full Article (PDF)	WJD-5-17.pdf
Full Article (Word)	WJD-5-17.doc
Manuscript File	6381-Review.doc
Answering Reviewers	6381-Answering reviewers.pdf
Copyright License Agreement	6381-Copyright assignment.pdf
Peer-review Report	6381-Peer review(s).pdf
Scientific Editor Work List	6381-Scientific editor work list.doc