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9/10/2021 12:09:57 PM | Browse: 26 | Download: 29
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 63986
Country/Territory China
Received
2021-02-06 18:57
Peer-Review Started
2021-02-06 19:05
To Make the First Decision
Return for Revision
2021-05-08 04:23
Revised
2021-06-01 14:53
Second Decision
2021-07-19 03:18
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-07-19 08:51
Articles in Press
2021-07-19 08:51
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-07-28 01:12
Typeset the Manuscript
2021-09-03 00:42
Publish the Manuscript Online
2021-09-10 12:09
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Meta-Analysis
Article Title Neoadjuvant chemotherapy without radiation as a potential alternative treatment for locally advanced rectal cancer: A meta-analysis
Manuscript Source Unsolicited Manuscript
All Author List Pei Wu, Hui-Mian Xu and Zhi Zhu
ORCID
Author(s) ORCID Number
Pei Wu http://orcid.org/0000-0002-5530-9633
Hui-Mian Xu http://orcid.org/0000-0002-1177-4445
Zhi Zhu http://orcid.org/0000-0001-6655-5189
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81302129
Corresponding Author Zhi Zhu, PhD, Doctor, Department of Surgical Oncology, The First Hospital of China Medical University, No. 155 Nanjing Street, Shenyang 110001, Liaoning Province, China. zhuzhi@cmu.edu.cn
Key Words Rectal cancer; Neoadjuvant chemotherapy; Chemoradiation; Prognosis
Core Tip Neoadjuvant chemoradiotherapy (Neo-CRT) acts as standard treatment in locally advanced rectal cancer (LARC), however, it delays the administration of optimal chemotherapy and increases toxicity. We design the meta-analysis aimed to compare the feasibility and efficacy of neoadjuvant chemotherapy (Neo-CT) vs Neo-CRT for the treatment of LARC. The present study showed that Neo-CT was effective for the treatment of LARC, especially to lower the incidences of anastomotic fistula and temporary colostomy, and increase the sphincter preservation rate as compared to Neo-CRT, and could have the potential to provide an alternative to chemoradiotherapy for LARC.
Publish Date 2021-09-10 12:09
Citation Wu P, Xu HM, Zhu Z. Neoadjuvant Chemotherapy without radiation as a potential alternative treatment for locally advanced rectal cancer: A meta-analysis. World J Gastrointest Oncol 2021; 13(9): 1196-1209
URL https://www.wjgnet.com/1948-5204/full/v13/i9/1196.htm
DOI https://dx.doi.org/10.4251/wjgo.v13.i9.1196
Full Article (PDF) WJGO-13-1196.pdf
Full Article (Word) WJGO-13-1196.docx
Manuscript File 63986-Review-FilipodiaCL.docx
Answering Reviewers 63986-Answering reviewers.pdf
Audio Core Tip 63986-Audio core tip.m4a
Biostatistics Review Certificate 63986-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 63986-Conflict-of-interest statement.pdf
Copyright License Agreement 63986-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 63986-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 63986-Language certificate.pdf
Peer-review Report 63986-Peer-review(s).pdf
Scientific Misconduct Check 63986-Bing-Ma YJ-1.jpg
Scientific Misconduct Check 63986-Bing-Liu M-2.jpg
Scientific Misconduct Check 63986-Scientific misconduct check.pdf
Scientific Editor Work List 63986-Scientific editor work list.pdf