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8/20/2021 10:31:42 AM | Browse: 319 | Download: 565
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 64229
Country/Territory Germany
Received
2021-02-12 12:24
Peer-Review Started
2021-02-12 12:28
To Make the First Decision
Return for Revision
2021-05-04 01:32
Revised
2021-05-12 20:16
Second Decision
2021-07-05 12:51
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-07-05 13:36
Articles in Press
2021-07-05 13:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-07-16 07:25
Typeset the Manuscript
2021-08-18 02:17
Publish the Manuscript Online
2021-08-20 10:31
ISSN 1948-9366 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Minireviews
Article Title Persistent bowel dysfunction after surgery for Hirschsprung’s disease: A neuropathological perspective
Manuscript Source Invited Manuscript
All Author List Sanne J Verkuijl, Florian Friedmacher, Patrick N Harter, Udo Rolle and Paul MA Broens
ORCID
Author(s) ORCID Number
Sanne J Verkuijl http://orcid.org/0000-0001-6995-7941
Florian Friedmacher http://orcid.org/0000-0002-7900-6004
Patrick N Harter http://orcid.org/0000-0001-5530-6910
Udo Rolle http://orcid.org/0000-0002-1268-6092
Paul MA Broens http://orcid.org/0000-0001-1234-1234
Funding Agency and Grant Number
Corresponding Author Sanne J Verkuijl, BSc, Research Fellow, Department of Pediatric Surgery, University Hospital Frankfurt, Goethe University Frankfurt, Theodor-Stern-Kai 7, Frankfurt 60590, Germany. s.j.verkuijl@umcg.nl
Key Words Hirschsprung disease; Aganglionosis; Proximal; Ganglionic; Constipation; Incontinence
Core Tip Hirschsprung’s disease (HD) is a congenital disorder, characterized by aganglionosis in the distal part of the gastrointestinal tract. Despite surgical resection of the aganglionic bowel segment, bowel dysfunction persists in a considerable number of patients with limited treatment options. There is growing evidence regarding structural abnormalities in the proximal, ganglionic colon of both humans and animals with HD, which may play a role in the persisting bowel dysfunction. Hence, understanding of these previously unrecognized neuropathological abnormalities in the proximal, ganglionic bowel of patients with HD may improve current follow-up and treatment of persisting postoperative bowel dysfunction in certain patients.
Publish Date 2021-08-20 10:31
Citation Verkuijl SJ, Friedmacher F, Harter PN, Rolle U, Broens PM. Persistent bowel dysfunction after surgery for Hirschsprung’s disease: A neuropathological perspective. World J Gastrointest Surg 2021; 13(8): 822-833
URL https://www.wjgnet.com/1948-9366/full/v13/i8/822.htm
DOI https://dx.doi.org/10.4240/wjgs.v13.i8.822
Full Article (PDF) WJGS-13-822.pdf
Full Article (Word) WJGS-13-822.docx
Manuscript File 64229_Auto_Edited-ZMG-Webster J_SV[23354]-Clear.docx
Answering Reviewers 64229-Answering reviewers.pdf
Audio Core Tip 64229-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 64229-Conflict-of-interest statement.pdf
Copyright License Agreement 64229-Copyright license agreement.pdf
Peer-review Report 64229-Peer-review(s).pdf
Scientific Misconduct Check 64229-Scientific misconduct check.pdf
Scientific Editor Work List 64229-Scientific editor work list.pdf