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10/13/2021 8:37:10 AM | Browse: 241 | Download: 477
Publication Name World Journal of Diabetes
Manuscript ID 64251
Country/Territory Mexico
Received
2021-02-25 03:02
Peer-Review Started
2021-02-25 03:05
To Make the First Decision
Return for Revision
2021-06-23 14:24
Revised
2021-07-28 00:22
Second Decision
2021-08-30 03:28
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-08-30 07:29
Articles in Press
2021-08-30 07:29
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-09-12 02:58
Typeset the Manuscript
2021-10-11 04:19
Publish the Manuscript Online
2021-10-13 08:37
ISSN 1948-9358 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Minireviews
Article Title Tale of two kinases: Protein kinase A and Ca2+/calmodulin-dependent protein kinase II in pre-diabetic cardiomyopathy
Manuscript Source Invited Manuscript
All Author List Pamela Gaitán-González, Rommel Sánchez-Hernández, José-Antonio Arias-Montaño and Angélica Rueda
ORCID
Author(s) ORCID Number
Pamela Gaitán-González http://orcid.org/0000-0002-8980-1212
Rommel Sánchez-Hernández http://orcid.org/0000-0002-4008-4179
José-Antonio Arias-Montaño http://orcid.org/0000-0002-0791-8397
Angélica Rueda http://orcid.org/0000-0001-8749-8494
Funding Agency and Grant Number
Funding Agency Grant Number
SEP-Cinvestav Project FIDSC 2018/2
SEP-Conacyt Ciencia Básica 2017-2018 A1-S-9082
Corresponding Author Angélica Rueda, PhD, Professor, Department of Biochemistry, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Av. IPN 2508, San Pedro Zacatenco, Ciudad de México 07360, Mexico. arueda@cinvestav.mx
Key Words Ca2+/calmodulin-dependent protein kinase II; Protein kinase A; Metabolic syndrome; Pre-diabetes; Pre-diabetic cardiomyopathy; β-Adrenoceptors
Core Tip Metabolic syndrome affects heart function leading to pre-diabetic cardiomyopathy. In an attempt to overcome contractility dysfunction, the activity of the sympathetic nervous system increases, but chronic stimulation of β-adrenoceptors leads to alterations in both protein kinase A (PKA) and Ca2+/calmodulin-dependent protein kinase II (CaMKII) activity, the main effectors of the β-adrenergic response. This work recapitulates current evidence about the participation of PKA and CaMKII in experimental pre-diabetic cardiomyopathy, emphasizing the prevailing role of CaMKII in the development of cardiomyocyte Ca2+ mishandling and myocardial dysfunction associated with pre-diabetes.
Publish Date 2021-10-13 08:37
Citation Gaitán-González P, Sánchez-Hernández R, Arias-Montaño JA, Rueda A. Tale of two kinases: Protein kinase A and Ca2+/calmodulin-dependent protein kinase II in pre-diabetic cardiomyopathy. World J Diabetes 2021; 12(10): 1704-1718
URL https://www.wjgnet.com/1948-9358/full/v12/i10/1704.htm
DOI https://dx.doi.org/10.4239/wjd.v12.i10.1704
Full Article (PDF) WJD-12-1704.pdf
Full Article (Word) WJD-12-1704.docx
Manuscript File 64251-Review-Filipodia-CL.docx
Answering Reviewers 64251-Answering reviewers.pdf
Audio Core Tip 64251-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 64251-Conflict-of-interest statement.pdf
Copyright License Agreement 64251-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 64251-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 64251-Language certificate.pdf
Peer-review Report 64251-Peer-review(s).pdf
Scientific Misconduct Check 64251-Scientific misconduct check.pdf
Scientific Editor Work List 64251-Scientific editor work list.pdf