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Articles Published Processes
1/18/2022 2:25:32 AM | Browse: 355 | Download: 565
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Received |
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2021-03-21 05:26 |
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Peer-Review Started |
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2021-03-21 05:29 |
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To Make the First Decision |
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Return for Revision |
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2021-05-01 04:19 |
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Revised |
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2021-05-15 13:51 |
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Second Decision |
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2021-12-16 03:49 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2021-12-23 06:29 |
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Articles in Press |
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2021-12-23 06:29 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-12-14 17:58 |
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Typeset the Manuscript |
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2022-01-06 03:00 |
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Publish the Manuscript Online |
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2022-01-18 02:25 |
| ISSN |
2150-5330 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Frontier |
| Article Title |
Molecular and genetic markers in hepatocellular carcinoma: In silico analysis to clinical validation (current limitations and future promises)
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Sarah El-Nakeep |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Sarah El-Nakeep, MD, Associate Professor, Gastroenterology and Hepatology Unit, Department of Internal Medicine, Faculty of Medicine, Ain Shams University, Ramsees street, Cairo 11591, Egypt. sarahnakeep@gmail.com |
| Key Words |
Hepatocellular carcinoma; In silico analysis; Bioinformatics; Biomarkers; Molecular pathways; Genetics; Epigenetics |
| Core Tip |
Hepatocellular carcinoma (HCC) is the second cause of cancer-related mortality. The importance of having an early detecting biomarker is to allow for curative measures to be applicable, and prognostic biomarkers to detect survival, in dealing with the disease. In silico analyses allow us to discover new genetic and epigenetic biomarkers, along with establishing the coexpression patterns, which impact HCC survival. Also, it allows for understanding the molecular pathways for HCC pathogenesis, and the discovery of potential therapeutic options. In this article, I review the current discoveries and limitations that face researchers to reach their ultimate goal of establishing clinical practice guidelines. I give an overview of the future potential that could benefit integrated research on HCC and discuss my own research related to the topic. |
| Publish Date |
2022-01-18 02:25 |
| Citation |
El-Nakeep S. Molecular and genetic markers in hepatocellular carcinoma: In silico analysis to clinical validation (current limitations and future promises). World J Gastrointest Pathophysiol 2022; 13(1): 1-14 |
| URL |
https://www.wjgnet.com/2150-5330/full/v13/i1/1.htm |
| DOI |
https://dx.doi.org/10.4291/wjgp.v13.i1.1 |
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