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8/12/2021 9:45:04 AM | Browse: 337 | Download: 684
Publication Name World Journal of Transplantation
Manuscript ID 64371
Country/Territory Japan
Received
2021-02-16 07:45
Peer-Review Started
2021-02-16 07:50
To Make the First Decision
Return for Revision
2021-05-14 00:21
Revised
2021-05-25 07:37
Second Decision
2021-08-10 03:00
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-08-10 06:05
Articles in Press
2021-08-10 06:05
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-08-12 00:32
Publish the Manuscript Online
2021-08-12 09:45
ISSN 2220-3230 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Minireviews
Article Title Biomarkers of graft-vs-host disease: Understanding and applications for the future
Manuscript Source Invited Manuscript
All Author List Masayuki Nagasawa
ORCID
Author(s) ORCID Number
Masayuki Nagasawa http://orcid.org/0000-0002-8085-4940
Funding Agency and Grant Number
Funding Agency Grant Number
Grant-in-Aid for Scientific Research (KAKENHI) Grant 15K09639
Corresponding Author Masayuki Nagasawa, MD, PhD, Chief Doctor, Department of Pediatrics, Musashino Red Cross Hospital, 1-26-1, Kyonan-cho, Musashino City 180-8610, Tokyo, Japan. mnagasawa.ped@tmd.ac.jp
Key Words Graft-vs-host disease; Hematopoietic stem cell transplantation; Biomarker; Cytokine; Graft-vs-host reaction; Organ damage
Core Tip Graft-vs-host disease (GVHD) is the most unfavorable complication of hematopoietic stem cell transplantation (HSCT). Minimizing acute GVHD and inducing its chronic form is necessary to achieve good clinical outcomes in HSCT. GVHD consists of inflammation induced by the conditioning regimen, the alloimmune response of the T lymphocytes, and organ damage due to the graft-vs-host reaction. Biological factors have been comprehensively analyzed to identify novel combinations of biomarkers that predict acute GVHD severity and prognosis more efficiently. Currently, there are no useful biomarkers that can predict the severity and prognosis of chronic GVHD or serve a practical clinical use.
Publish Date 2021-08-12 09:45
Citation Nagasawa M. Biomarkers of graft-vs-host disease: Understanding and applications for the future. World J Transplant 2021;11(8): 335-343
URL https://www.wjgnet.com/2220-3230/full/v11/i8/335.htm
DOI https://dx.doi.org/10.5500/wjt.v11.i8.335
Full Article (PDF) WJT-11-335.pdf
Full Article (Word) WJT-11-335.docx
Manuscript File 64371_Auto_Edited-JPY.docx
Answering Reviewers 64371-Answering reviewers.pdf
Audio Core Tip 64371-Audio core tip.MP3
Conflict-of-Interest Disclosure Form 64371-Conflict-of-interest statement.pdf
Copyright License Agreement 64371-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 64371-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 64371-Language certificate.pdf
Peer-review Report 64371-Peer-review(s).pdf
Scientific Misconduct Check 64371-Bing-W JJ-2.png
Scientific Misconduct Check 64371-Scientific misconduct check.pdf
Scientific Editor Work List 64371-Scientific editor work list.pdf