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10/13/2021 12:57:54 PM | Browse: 21 | Download: 12
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 64402
Country/Territory Greece
2021-02-16 18:20
Peer-Review Started
2021-02-16 18:24
To Make the First Decision
Return for Revision
2021-03-29 21:19
2021-04-06 21:15
Second Decision
2021-08-02 02:49
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-08-02 07:42
Articles in Press
2021-08-02 07:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-08-15 23:59
Typeset the Manuscript
2021-09-30 08:32
Publish the Manuscript Online
2021-10-13 12:57
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Review
Article Title Role of autophagy in gastric carcinogenesis
Manuscript Source Invited Manuscript
All Author List Apostolis Papaefthymiou, Gregory Christodoulidis, Apostolos Koffas, Michael Doulberis, Stergios A Polyzos, Anastasios Manolakis, Spyros Potamianos, Andreas Kapsoritakis and Jannis Kountouras
Author(s) ORCID Number
Apostolis Papaefthymiou http://orcid.org/0000-0002-3563-4973
Gregory Christodoulidis http://orcid.org/0000-0003-3413-0666
Apostolos Koffas http://orcid.org/0000-0002-2637-3847
Michael Doulberis http://orcid.org/0000-0002-0396-5081
Stergios A Polyzos http://orcid.org/0000-0001-9232-4042
Anastasios Manolakis http://orcid.org/0000-0001-8661-6997
Spyros Potamianos http://orcid.org/0000-0001-8661-6999
Andreas Kapsoritakis http://orcid.org/0000-0001-8661-6991
Jannis Kountouras http://orcid.org/0000-0001-6459-5136
Funding Agency and Grant Number
Corresponding Author Apostolis Papaefthymiou, MD, PhD, N/A, Department of Gastroenterology, University Hospital of Larissa, Mezourlo, Larissa 41110, Thessaly, Greece. appapaef@hotmail.com
Key Words Gastric cancer; Autophagy; Helicobacter pylori; Chemoresistance; Prognosis
Core Tip Autophagy comprises a substantial normal cellular function, implicated in benign and malignant diseases. Its complex regulatory system can be affected at any stage by endogenous and environmental factors. Helicobacter pylori expresses and stimulates a wide range of autophagy modulators, thus promoting or inhibiting autophagy to yield a survival benefit and cause damage. Concerning gastric cancer, the dysregulated autophagic process facilitates tumor generation, progress and resistance to chemotherapy, through various mechanisms. The current review attempts to decrypt and simplify those mechanisms and the respective pathways, to explain their promising potential for the development of therapeutic agents and prognostic tools.
Publish Date 2021-10-13 12:57
Citation Papaefthymiou A, Christodoulidis G, Koffas A, Doulberis M, Polyzos SA, Manolakis A, Potamianos S, Kapsoritakis A, Kountouras J. Role of autophagy in gastric carcinogenesis. World J Gastrointest Oncol 2021; 13(10): 1244-1262
URL https://www.wjgnet.com/1948-5204/full/v13/i10/1244.htm
DOI https://dx.doi.org/10.4251/wjgo.v13.i10.1244
Full Article (PDF) WJGO-13-1244.pdf
Full Article (Word) WJGO-13-1244.docx
Manuscript File 64402-Review-FilipodiaCL.docx
Answering Reviewers 64402-Answering reviewers.pdf
Audio Core Tip 64402-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 64402-Conflict-of-interest statement.pdf
Copyright License Agreement 64402-Copyright license agreement.pdf
Peer-review Report 64402-Peer-review(s).pdf
Scientific Misconduct Check 64402-Bing-Wang JL-1.jpg
Scientific Misconduct Check 64402-Scientific misconduct check.pdf
Scientific Editor Work List 64402-Scientific editor work list.pdf