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9/9/2021 9:23:46 AM | Browse: 348 | Download: 541
Publication Name World Journal of Critical Care Medicine
Manuscript ID 64472
Country/Territory Australia
Received
2021-02-21 06:04
Peer-Review Started
2021-02-21 06:07
To Make the First Decision
Return for Revision
2021-05-13 23:54
Revised
2021-05-18 01:15
Second Decision
2021-07-27 03:26
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-07-27 07:38
Articles in Press
2021-07-27 07:38
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-09-07 10:52
Publish the Manuscript Online
2021-09-09 09:23
ISSN 2220-3141(online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Critical Care Medicine
Manuscript Type Systematic Reviews
Article Title Neutrophil kinetics and function after major trauma: A systematic review
Manuscript Source Invited Manuscript
All Author List Liam DB Finlay, Andrew Conway Morris, Adam Deane and Alexander JT Wood
ORCID
Author(s) ORCID Number
Liam DB Finlay http://orcid.org/0000-0003-0820-0712
Andrew Conway Morris http://orcid.org/0000-0002-3211-3216
Adam Deane http://orcid.org/0000-0002-7620-5577
Alexander JT Wood http://orcid.org/0000-0001-7819-0447
Funding Agency and Grant Number
Funding Agency Grant Number
Wellcome Trust WT 205214/Z/16/Z
National Health and Medical Research Council (Australia) APP1141870
MRC Clinician Scientist Fellowship MR/V006118/1
Corresponding Author Alexander JT Wood, MBBS, PhD, Doctor, Intensive Care Unit, Royal Melbourne Hospital, Intensive Care Unit Offices Level 5, B Block Royal Melbourne Hospital 300 Grattan Street , Parkville 3052, Victoria, Australia. alex.wood1@unimelb.edu.au
Key Words Neutrophils; Multiple trauma; Immunophenotypes; Inflammation; Systemic inflammatory response syndrome; Intensive care units
Core Tip Major trauma results in complex immune dysfunction, with dysregulated pro- and anti-inflammatory processes presenting as clinical syndromes such as acute respiratory distress syndrome (ARDS) and multiple organ dysfunction syndrome (MODS). This review examines the role of neutrophils in immune dysfunction following major trauma requiring admission to the intensive care unit, with a focus on the kinetics of the neutrophil immunophenotype and how this correlates with clinical outcomes. This review also proposes new hypotheses as to the mechanisms of complications of immune dysfunction, including ARDS and MODS.
Publish Date 2021-09-09 09:23
Citation Finlay LD, Conway Morris A, Deane A, Wood AJ. Neutrophil kinetics and function after major trauma: A systematic review. World J Crit Care Med 2021; 10(5): 260-277
URL https://www.wjgnet.com/2220-3141/full/v10/i5/260.htm
DOI https://dx.doi.org/10.5492/wjccm.v10.i5.260
Full Article (PDF) wjccm-10-260.pdf
Full Article (Word) WJCCM-10-260.docx
PRISMA 2009 Checklist 64472-PRISMA-2009-Checklist-revision.pdf
Manuscript File 64472_Auto_Edited-JPY.docx
Answering Reviewers 64472-Answering reviewers.pdf
Audio Core Tip 64472-Audio core tip.m4a
Biostatistics Review Certificate 64472-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 64472-Conflict-of-interest statement.pdf
Copyright License Agreement 64472-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 64472-Figure(s).pptx
Supplementary Material 64472-Supplementary material.pdf
Peer-review Report 64472-Peer-review(s).pdf
Scientific Misconduct Check 64472-Bing-Wang JL-1.jpg
Scientific Misconduct Check 64472-Bing-Wang LL-2.png
Scientific Misconduct Check 64472-Scientific misconduct check.pdf
Scientific Editor Work List 64472-Scientific editor work list.pdf