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7/7/2021 8:39:46 AM | Browse: 275 | Download: 537
Publication Name World Journal of Clinical Cases
Manuscript ID 64741
Country/Territory Brazil
Received
2021-02-23 01:40
Peer-Review Started
2021-02-23 01:42
To Make the First Decision
Return for Revision
2021-03-28 16:06
Revised
2021-04-03 20:02
Second Decision
2021-05-25 09:51
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-05-25 11:34
Articles in Press
2021-05-25 11:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-05-31 02:46
Typeset the Manuscript
2021-06-19 09:35
Publish the Manuscript Online
2021-07-07 08:39
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Systematic Reviews
Article Title Herb-induced liver injury: Systematic review and meta-analysis
Manuscript Source Invited Manuscript
All Author List Vinícius Remus Ballotin, Lucas Goldmann Bigarella, Ajacio Bandeira de Mello Brandão, Raul Angelo Balbinot, Silvana Sartori Balbinot and Jonathan Soldera
ORCID
Author(s) ORCID Number
Vinícius Remus Ballotin http://orcid.org/0000-0002-2659-2249
Lucas Goldmann Bigarella http://orcid.org/0000-0001-8087-0070
Ajacio Bandeira de Mello Brandão http://orcid.org/0000-0001-8411-5654
Raul Angelo Balbinot http://orcid.org/0000-0003-4705-0702
Silvana Sartori Balbinot http://orcid.org/0000-0002-5026-1028
Jonathan Soldera http://orcid.org/0000-0001-6055-4783
Funding Agency and Grant Number
Corresponding Author Jonathan Soldera, MD, MSc, Associate Professor, Staff Physician, Department of Clinical Gastroenterology, Universidade de Caxias do Sul, Rua Francisco Getúlio Vargas, 1130, Caxias do Sul 95070-560, RS, Brazil. jonathansoldera@gmail.com
Key Words Herb-induced liver injury; Drug induced liver injury; Dietary supplements; Herbal hepatotoxicity; Liver transplantation
Core Tip The use of herbal supplements has been increasing in the last decades. Despite popular belief that natural products are harmless, these might cause herb-induced liver injury (HILI). This study aimed to identify herbal products associated with HILI. The search strategy retrieved 5918 references. In the final analysis, 446 references were included, with a total of 936 cases reported. We found 79 types of herbs related to HILI. Most of these patients had complete clinical recovery (82.8%). However, liver transplantation was necessary for 6.6% of these cases. Also, chronic liver disease and death were observed in 1.5% and 10.4%, respectively.
Publish Date 2021-07-07 08:39
Citation Ballotin VR, Bigarella LG, Brandão ABM, Balbinot RA, Balbinot SS, Soldera J. Herb-induced liver injury: Systematic review and meta-analysis. World J Clin Cases 2021; 9(20): 5490-5513
URL https://www.wjgnet.com/2307-8960/full/v9/i20/5490.htm
DOI https://dx.doi.org/10.12998/wjcc.v9.i20.5490
Full Article (PDF) WJCC-9-5490.pdf
Full Article (Word) WJCC-9-5490.docx
PRISMA 2009 Checklist 64741-PRISMA-2009-Checklist-revision.pdf
Manuscript File 64741-Review-Filipodia-CL.docx
Answering Reviewers 64741-Answering reviewers.pdf
Audio Core Tip 64741-Audio core tip.mp3
Biostatistics Review Certificate 64741-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 64741-Conflict-of-interest statement.pdf
Copyright License Agreement 64741-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 64741-Language certificate.pdf
Supplementary Material 64741-Supplementary material.pdf
Peer-review Report 64741-Peer-review(s).pdf
Scientific Misconduct Check 64741-Bing-Wang JL-1.jpg
Scientific Misconduct Check 64741-Scientific misconduct check.pdf
Scientific Editor Work List 64741-Scientific editor work list.pdf