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1/20/2022 10:47:59 AM | Browse: 273 | Download: 723
Publication Name World Journal of Stem Cells
Manuscript ID 64813
Country/Territory Egypt
Received
2021-02-26 06:35
Peer-Review Started
2021-02-26 06:39
To Make the First Decision
Return for Revision
2021-06-24 23:17
Revised
2021-07-02 22:21
Second Decision
2022-01-05 03:28
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-01-06 19:44
Articles in Press
2022-01-06 19:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-01-13 04:21
Publish the Manuscript Online
2022-01-20 10:47
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cardiac & Cardiovascular Systems
Manuscript Type Review
Article Title Cardiac stem cells: Current knowledge and future prospects
Manuscript Source Invited Manuscript
All Author List Radwa Ali Mehanna, Marwa M Essawy, Mona A Barkat, Ashraf K Awaad, Eman H Thabet, Heba A Hamed, Hagar Elkafrawy, Nehal A Khalil, Abeer Sallam, Marwa A Kholief, Samar S Ibrahim and Ghada M Mourad
ORCID
Author(s) ORCID Number
Radwa Ali Mehanna http://orcid.org/0000-0001-9048-4464
Marwa M Essawy http://orcid.org/0000-0002-4781-4293
Mona A Barkat http://orcid.org/0000-0003-3850-0193
Ashraf K Awaad http://orcid.org/0000-0001-8285-0188
Eman H Thabet http://orcid.org/0000-0003-3490-3825
Heba A Hamed http://orcid.org/0000-0001-8080-4620
Hagar Elkafrawy http://orcid.org/0000-0002-1591-1689
Nehal A Khalil http://orcid.org/0000-0001-9380-7425
Abeer Sallam http://orcid.org/0000-0002-4690-6348
Marwa A Kholief http://orcid.org/0000-0001-8776-5257
Samar S Ibrahim http://orcid.org/0000-0002-5547-9667
Ghada M Mourad http://orcid.org/0000-0002-6145-3076
Funding Agency and Grant Number
Funding Agency Grant Number
Science, Technology & Innovation Funding Authority STIFA 28932
Cardiovascular Research, Education, Prevention Foundation (CVREP)
Corresponding Author Radwa Ali Mehanna, MD, PhD, Academic Research, Associate Professor, Executive Vice President, Medical Physiology Department/Center of Excellence for Research in Regenerative Medicine and Applications, Faculty of Medicine, Alexandria University, Al Khartoum Square, Azareeta, Alexandria 21500, Egypt. radwa.mehanna@alexmed.edu.eg
Key Words Cardiac stem and progenitor cells; Cardiac stem cells’ secretome; Cardiac stem cells’ niche and metabolism; Nanotechnology; Clinical trials; Combined therapy
Core Tip With the growing evidence for the existence of regenerating cardiac stem and progenitor cells, studies to evaluate their therapeutic potential have received increasing attention. Although pre-clinical research and clinical trials have demonstrated promising results, yet the latter were often inconsistent in many aspects thus imposing the need for deeper exploration of the molecular biology and relevant pathways regulating cardiogenesis and cardiac muscle repair. This review gives an insight into cardiac stem and progenitor cells regarding their embryological origin, populations, niche, secretome, and metabolism. It overviews the current preclinical research, including medical nanotechnology, and the clinical trials generally applied for cardiac regeneration.
Publish Date 2022-01-20 10:47
Citation Mehanna RA, Essawy MM, Barkat MA, Awaad AK, Thabet EH, Hamed HA, Elkafrawy H, Khalil NA, Sallam A, Kholief MA, Ibrahim SS, Mourad GM. Cardiac stem cells: Current knowledge and future prospects. World J Stem Cells 2022; 14(1): 1-40
URL https://www.wjgnet.com/1948-0210/full/v14/i1/1.htm
DOI https://dx.doi.org/10.4252/wjsc.v14.i1.1
Full Article (PDF) WJSC-14-1.pdf
Full Article (Word) WJSC-14-1.docx
Manuscript File 64813_Auto_Edited.docx
Answering Reviewers 64813-Answering reviewers.pdf
Audio Core Tip 64813-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 64813-Conflict-of-interest statement.pdf
Copyright License Agreement 64813-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 64813-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 64813-Language certificate.pdf
Peer-review Report 64813-Peer-review(s).pdf
Scientific Misconduct Check 64813-CrossCheck.jpg
Scientific Misconduct Check 64813-Bing-Gong ZM-2.png
Scientific Editor Work List 64813-Scientific editor work list.pdf