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10/15/2021 9:56:18 AM | Browse: 207 | Download: 180
Publication Name World Journal of Psychiatry
Manuscript ID 64823
Country/Territory Australia
2021-02-24 00:15
Peer-Review Started
2021-02-24 00:18
To Make the First Decision
Return for Revision
2021-07-04 02:37
2021-07-19 07:07
Second Decision
2021-08-25 03:16
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-08-25 05:45
Articles in Press
2021-08-25 05:45
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-10-08 07:49
Publish the Manuscript Online
2021-10-15 09:56
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Review
Article Title Alternative models for transgenerational epigenetic inheritance: Molecular psychiatry beyond mice and man
Manuscript Source Invited Manuscript
All Author List Gary R Hime, Sophie LA Stonehouse and Terence Y Pang
Author(s) ORCID Number
Gary R Hime http://orcid.org/0000-0003-4732-3184
Sophie LA Stonehouse http://orcid.org/0000-0003-2935-0963
Terence Y Pang http://orcid.org/0000-0002-7000-5304
Funding Agency and Grant Number
Corresponding Author Terence Y Pang, PhD, Senior Postdoctoral Fellow, Mental Health Theme, The Florey Institute of Neuroscience and Mental Health, 30 Royal Parade , Parkville 3052, VIC, Australia. terence.pang@florey.edu.au
Key Words Transgenerational inheritance; Epigenetics; Invertebrate models; Caenorhabditis elegans; Drosophila melanogaster; Environmental stress
Core Tip Psychiatry research is only beginning to identify the complex epigenetic pathologies across various conditions that may regulate symptomatology. Epigenetics may account for certain conditions that are highly heritable but are not fully accounted for by genetics. Preclinical animal models are a necessary tool to accelerate our understanding of molecular mechanisms and for developing new therapeutic options. Simple behavioural and neurobiological assays combined with high levels of functional gene conservation and rapid generation time in easily genetically manipulated organisms make Caenorhabditis elegans and Drosophila melanogaster excellent systems to model transgenerational epigenetic inheritance phenotypes.
Publish Date 2021-10-15 09:56
Citation Hime GR, Stonehouse SLA, Pang TY. Alternative models for transgenerational epigenetic inheritance: Molecular psychiatry beyond mice and man. World J Psychiatr 2021; 11(10): 711-735
URL https://www.wjgnet.com/2220-3206/full/v11/i10/711.htm
DOI https://dx.doi.org/10.5498/wjp.v11.i10.711
Full Article (PDF) WJP-11-711.pdf
Full Article (Word) WJP-11-711.docx
Manuscript File 64823_Auto_Edited-JPY.docx
Answering Reviewers 64823-Answering reviewers.pdf
Audio Core Tip 64823-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 64823-Conflict-of-interest statement.pdf
Copyright License Agreement 64823-Copyright license agreement.pdf
Peer-review Report 64823-Peer-review(s).pdf
Scientific Misconduct Check 64823-Bing-Fan JR-2.png
Scientific Misconduct Check 64823-Scientific misconduct check.pdf
Scientific Editor Work List 64823-Scientific editor work list.pdf