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Articles Published Processes
6/7/2021 11:17:20 AM | Browse: 335 | Download: 410
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Received |
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2021-02-25 05:15 |
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Peer-Review Started |
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2021-02-25 05:20 |
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To Make the First Decision |
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Return for Revision |
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2021-04-19 04:47 |
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Revised |
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2021-04-22 05:19 |
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Second Decision |
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2021-05-08 09:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2021-05-08 10:02 |
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Articles in Press |
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2021-05-08 10:02 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-05-31 01:02 |
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Publish the Manuscript Online |
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2021-06-07 11:17 |
ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Minireviews |
Article Title |
Poly adenosine diphosphate-ribosylation, a promising target for colorectal cancer treatment
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Manuscript Source |
Invited Manuscript |
All Author List |
Keun-Yeong Jeong and Minhee Park |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Keun-Yeong Jeong, PhD, Executive Vice President, Research Assistant Professor, Research and Development, Metimedi Pharmaceuticals, 263 Central-ro, Incheon 22006, South Korea. alvirus@naver.com |
Key Words |
Colorectal cancer; Poly adenosine diphosphate-ribose polymerase-1; Poly adenosine diphosphate-ribose; Poly-adenosine diphosphate ribosylation |
Core Tip |
The main focus is on highlighting the pivotal role of poly adenosine diphosphate-ribose polymerase-1 (PARP-1) and poly-adenosine diphosphate ribosylation (PARylation) in regulating deoxyribonucleic acid damage response, redox homeostasis, chromosomal instability, and transcriptional activity under the common denominator of overcoming the genomic instability in colorectal cancer (CRC). The importance of targeting PARP-1 and PARylation in the treatment of CRC will be emphasized because the level of understanding of pathological changes leading to malignant transformation of CRC by PARP-1 and PARylation may increase. |
Publish Date |
2021-06-07 11:17 |
Citation |
Jeong KY, Park M. Poly adenosine diphosphate-ribosylation, a promising target for colorectal cancer treatment. World J Gastrointest Oncol 2021; 13(6): 574-588 |
URL |
https://www.wjgnet.com/1948-5204/full/v13/i6/574.htm |
DOI |
https://dx.doi.org/10.4251/wjgo.v13.i6.574 |
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