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12/15/2021 9:38:23 AM | Browse: 248 | Download: 334
Publication Name World Journal of Psychiatry
Manuscript ID 64937
Country/Territory China
Received
2021-03-01 04:19
Peer-Review Started
2021-03-01 04:21
To Make the First Decision
Return for Revision
2021-07-15 03:02
Revised
2021-07-29 18:45
Second Decision
2021-11-02 03:56
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-11-03 01:23
Articles in Press
2021-11-03 01:23
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-10-14 09:41
Typeset the Manuscript
2021-12-10 00:21
Publish the Manuscript Online
2021-12-15 09:38
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Psychiatry
Manuscript Type Review
Article Title Nuclear receptors modulate inflammasomes in the pathophysiology and treatment of major depressive disorder
Manuscript Source Invited Manuscript
All Author List Han Wang, Wei-Jing Kan, Yuan Feng, Lei Feng, Yang Yang, Pei Chen, Jing-Jie Xu, Tian-Mei Si, Ling Zhang, Gang Wang and Jing Du
ORCID
Author(s) ORCID Number
Han Wang http://orcid.org/0000-0001-9366-1817
Wei-Jing Kan http://orcid.org/0000-0002-1538-7047
Yuan Feng http://orcid.org/0000-0003-4172-4024
Lei Feng http://orcid.org/0000-0001-7810-5070
Yang Yang http://orcid.org/0000-0001-8425-6633
Pei Chen http://orcid.org/0000-0002-6396-1031
Jing-Jie Xu http://orcid.org/0000-0001-8311-2355
Tian-Mei Si http://orcid.org/0000-0001-9823-2720
Ling Zhang http://orcid.org/0000-0002-9713-1458
Gang Wang http://orcid.org/0000-0003-3949-1188
Jing Du http://orcid.org/0000-0003-3128-9997
Funding Agency and Grant Number
Funding Agency Grant Number
the National Natural Science Foundation of China 31650005
Corresponding Author Jing Du, PhD, Professor, The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, No. 5 Ankanghuton, Western City District , Beijing 100088, Beijing Province, China. 2648215772@qq.com
Key Words Major depressive disorder; Immune inflammation; Inflammasome; Nuclear receptors
Core Tip We summarize the evidence on nuclear receptors (NRs), such as glucocorticoid receptor, mineralocorticoid receptor, estrogen receptor, aryl hydrocarbon receptor, and peroxisome proliferator-activated receptor, in modulating inflammasome activity and depression-associated behaviors. This review provides evidence from an endocrine perspective to understand the role of activated NRs in the pathophysiology and treatment of major depressive disorder. Hopefully, the modulation of NRs with hormones and metabolites may become one of the key endocrinologic mechanisms for the development of novel therapeutics to increase the likelihood of therapeutic efficacy.
Publish Date 2021-12-15 09:38
Citation Wang H, Kan WJ, Feng Y, Feng L, Yang Y, Chen P, Xu JJ, Si TM, Zhang L, Wang G, Du J. Nuclear receptors modulate inflammasomes in the pathophysiology and treatment of major depressive disorder. World J Psychiatr 2021; 11(12): 1191-1205
URL https://www.wjgnet.com/2220-3206/full/v11/i12/1191.htm
DOI https://dx.doi.org/10.5498/wjp.v11.i12.1191
Full Article (PDF) WJP-11-1191.pdf
Full Article (Word) WJP-11-1191.docx
Manuscript File 64937_Auto_Edited-JJ Wang-WangTQ.docx
Answering Reviewers 64937-Answering reviewers.pdf
Audio Core Tip 64937-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 64937-Conflict-of-interest statement.pdf
Copyright License Agreement 64937-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 64937-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 64937-Language certificate.pdf
Supplementary Material 64937-Supplementary material.pdf
Peer-review Report 64937-Peer-review(s).pdf
Scientific Misconduct Check 64937-Bing-Wang JJ-2.png
Scientific Editor Work List 64937-Scientific editor work list.pdf