| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Hepatitis C: Problems to extinction and residual hepatic and extrahepatic lesions after sustained virological response
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Sara Cuesta-Sancho, Mercedes Márquez-Coello, Francisco Illanes-Álvarez, Denisse Márquez-Ruiz, Ana Arizcorreta, Fátima Galán-Sánchez, Natalia Montiel, Manuel Rodriguez-Iglesias and José-Antonio Girón-González |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Consejería de Salud, Junta de Andalucía, Integrated Territorial Initiative for the province of Cádiz |
(ITI) 2014-2020 |
| Fondo Europeo de Desarrollo Regional (FEDER) |
PI-0076-2017 |
| Consejería de Salud, Junta de Andalucía |
PI 0128/2018 |
| Instituto de Salud Carlos III, Ministerio de Sanidad, Acción Estratégica en Salud 2017-2020 |
PI19/01361 |
|
| Corresponding Author |
José-Antonio Girón-González, MD, PhD, Doctor, Medicina Interna, Hospital Universitario Puerta del Mar, Facultad de Medicina, Universidad de Cádiz, Instituto para la Investigación e Innovación en Ciencias Biomédicas de Cádiz (INiBICA), Avda Ana de Viya, s/n, Cádiz 11009, Spain. joseantonio.giron@uca.es |
| Key Words |
Hepatitis C virus; Sustained virological response; Direct antiviral agents; Human immunodeficiency virus; Cirrhosis decompensation; Hepatocarcinoma; Extrahepatic complications |
| Core Tip |
The excellent hepatitis C virus (HCV) response to direct acting agents should not obviate certain obstacles to eradicate this pathology, especially the loss to follow-up and the possibility of reinfections. Chronic hepatitis C determines persistent alterations despite the elimination of HCV, such as liver dysfunction and continued risk of decompensation and hepatocarcinoma, especially in subjects treated in advanced stages of the disease. Weight gain after sustained virological response (SVR) may favor liver steatosis, increasing the risk of progression of hepatic disease. The probability of complications after SVR in human immunodeficiency virus coinfected patients is similar to that of those HCV-monoinfected. |
| Publish Date |
2022-01-21 08:16 |
| Citation |
Cuesta-Sancho S, Márquez-Coello M, Illanes-Álvarez F, Márquez-Ruiz D, Arizcorreta A, Galán-Sánchez F, Montiel N, Rodriguez-Iglesias M, Girón-González JA. Hepatitis C: Problems to extinction and residual hepatic and extrahepatic lesions after sustained virological response. World J Hepatol 2022; 14(1): 62-79 |
| URL |
https://www.wjgnet.com/1948-5182/full/v14/i1/62.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v14.i1.62 |
