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6/8/2021 10:51:03 AM | Browse: 14 | Download: 27
Publication Name World Journal of Gastroenterology
Manuscript ID 65462
Country/Territory China
Received
2021-03-07 17:57
Peer-Review Started
2021-03-07 18:01
To Make the First Decision
Return for Revision
2021-03-27 17:50
Revised
2021-04-09 07:41
Second Decision
2021-04-28 07:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-04-28 08:19
Articles in Press
2021-04-28 08:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-05-10 14:32
Typeset the Manuscript
2021-06-03 06:01
Publish the Manuscript Online
2021-06-08 10:51
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Basic Study
Article Title Enhancer of zeste homolog 2 contributes to apoptosis by inactivating JAK2/STAT signaling in inflammatory bowel disease
Manuscript Source Unsolicited Manuscript
All Author List Jie Zhou, Yang Yang, Yi-Ling Wang, Yue Zhao, Wen-Jing Ye, Si-Yao Deng, Jin-Yi Lang and Shun Lu
ORCID
Author(s) ORCID Number
Jie Zhou http://orcid.org/0000-0003-4559-1767
Yang Yang http://orcid.org/0000-0002-9148-5757
Yi-Ling Wang http://orcid.org/0000-0003-4344-8844
Yue Zhao http://orcid.org/0000-0002-6319-5429
Wen-Jing Ye http://orcid.org/0000-0003-1310-8304
Si-Yao Deng http://orcid.org/0000-0002-0575-5408
Jin-Yi Lang http://orcid.org/0000-0001-6353-4972
Shun Lu http://orcid.org/0000-0002-3241-6591
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81900498
Corresponding Author Shun Lu, MD, Chief Physician, Department of Radiation Oncology, Sichuan Cancer Hospital, No. 55 Renmin South Road, Chengdu 610041, Sichuan Province, China. lushousi90036@163.com
Key Words Inflammatory bowel disease; Apoptosis; Enhancer of zeste homolog 2; JAK2; Permeability; Inflammatory bowel disease therapy
Core Tip In this study, we discovered that enhancer of zeste homolog 2 (EZH2) contributed to apoptosis and inflammatory response by inactivating JAK2/STAT signaling in inflammatory bowel disease (IBD). EZH2 may be applied as the potential targets for IBD therapy.
Publish Date 2021-06-08 10:51
Citation Zhou J, Yang Y, Wang YL, Zhao Y, Ye WJ, Deng SY, Lang JY, Lu S. Enhancer of zeste homolog 2 contributes to apoptosis by inactivating JAK2/STAT signaling in inflammatory bowel disease. World J Gastroenterol 2021; 27(22): 3073-3084
URL https://www.wjgnet.com/1007-9327/full/v27/i22/3073.htm
DOI https://dx.doi.org/10.3748/wjg.v27.i22.3073
Full Article (PDF) WJG-27-3073.pdf
Full Article (Word) WJG-27-3073.docx
Manuscript File 65462-Review-FilipodiaCL.docx
Answering Reviewers 65462-Answering reviewers.pdf
Audio Core Tip 65462-Audio core tip.mp3
Biostatistics Review Certificate 65462-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 65462-Conflict-of-interest statement.pdf
Copyright License Agreement 65462-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 65462-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 65462-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 65462-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 65462-Language certificate.pdf
Peer-review Report 65462-Peer-review(s).pdf
Scientific Misconduct Check 65462-Bing Liu M-1.png
Scientific Misconduct Check 65462-Bing-Fan JR-2.png
Scientific Misconduct Check 65462-Scientific misconduct check.pdf
Scientific Editor Work List 65462-Scientific editor work list.pdf