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7/15/2021 10:19:10 AM | Browse: 467 | Download: 837
Publication Name World Journal of Psychiatry
Manuscript ID 65474
Country/Territory Nigeria
Received
2021-03-07 21:56
Peer-Review Started
2021-03-07 22:01
To Make the First Decision
Return for Revision
2021-03-30 04:16
Revised
2021-04-13 21:37
Second Decision
2021-05-10 09:35
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-05-10 09:56
Articles in Press
2021-05-10 09:56
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-06-07 04:56
Typeset the Manuscript
2021-06-30 09:49
Publish the Manuscript Online
2021-07-15 10:19
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Neurosciences
Manuscript Type Review
Article Title Glutamate and depression: Reflecting a deepening knowledge of the gut and brain effects of a ubiquitous molecule
Manuscript Source Invited Manuscript
All Author List Adejoke Yetunde Onaolapo and Olakunle James Onaolapo
ORCID
Author(s) ORCID Number
Adejoke Yetunde Onaolapo http://orcid.org/0000-0001-7126-7050
Olakunle James Onaolapo http://orcid.org/0000-0003-2142-6046
Funding Agency and Grant Number
Corresponding Author Olakunle James Onaolapo, MBBS, MSc, PhD, Senior Lecturer, Behavioural Neuroscience Unit, Neuropharmacology Subdivision, Department of Pharmacology, Ladoke Akintola University of Technology, P.M.B 4000, Osun State 234, Nigeria. olakunleonaolapo@yahoo.co.uk
Key Words Brain; Gut microbiome; Mental health; Mood disorders; Neurotransmitters
Core Tip The versatility of glutamate as the brain’s foremost excitatory neurotransmitter, and modulator of intermediary metabolism in the gastrointestinal tract is considered common knowledge. Years of research suggest glutamate has a role to play in depression. Also, there is increasing evidence of a possible relationship between glutamate and the pathophysiology and/or treatment of depression. The complexity of depression suggests dysregulation of glutamate in sites such as the gastrointestinal tract and brain. The communication link involving dietary glutamate, the gut, endogenous glutamate, and the brain is a multidirectional pathway; the understanding of which is necessary to fully account for glutamate’s role in depression.
Publish Date 2021-07-15 10:19
Citation Onaolapo AY, Onaolapo OJ. Glutamate and depression: Reflecting a deepening knowledge of the gut and brain effects of a ubiquitous molecule. World J Psychiatr 2021; 11(7): 297-315
URL https://www.wjgnet.com/2220-3206/full/v11/i7/297.htm
DOI https://dx.doi.org/10.5498/wjp.v11.i7.297
Full Article (PDF) WJP-11-297.pdf
Full Article (Word) WJP-11-297.docx
Manuscript File 65474_Auto_Edited-ZMG-Webster__ J[22938]-Clear.docx
Answering Reviewers 65474-Answering reviewers.pdf
Audio Core Tip 65474-Audio core tip.wma
Conflict-of-Interest Disclosure Form 65474-Conflict-of-interest statement.pdf
Copyright License Agreement 65474-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 65474-Language certificate.pdf
Peer-review Report 65474-Peer-review(s).pdf
Scientific Misconduct Check 65474-Bing-Liu M-1.png
Scientific Misconduct Check 65474-Scientific misconduct check.pdf
Scientific Editor Work List 65474-Scientific editor work list.pdf