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7/12/2021 12:42:14 AM | Browse: 332 | Download: 550
Publication Name World Journal of Gastroenterology
Manuscript ID 65488
Country China
Received
2021-03-08 10:05
Peer-Review Started
2021-03-08 10:09
To Make the First Decision
Return for Revision
2021-04-17 13:26
Revised
2021-04-27 07:23
Second Decision
2021-06-16 13:31
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-06-16 13:59
Articles in Press
2021-06-16 13:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-06-23 04:36
Typeset the Manuscript
2021-07-07 04:15
Publish the Manuscript Online
2021-07-12 00:42
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Basic Study
Article Title Ubiquitin-specific protease 15 contributes to gastric cancer progression via regulating the Wnt/β-catenin signaling pathway
Manuscript Source Unsolicited Manuscript
All Author List Min Zhong, Ling Zhou, Zhi Fang, Yang-Yang Yao, Jian-Ping Zou, Jian-Ping Xiong, Xiao-Jun Xiang and Jun Deng
ORCID
Author(s) ORCID Number
Min Zhong http://orcid.org/0000-0001-5423-0918
Ling Zhou http://orcid.org/0000-0002-2131-1751
Zhi Fang http://orcid.org/0000-0002-5612-0963
Yang-Yang Yao http://orcid.org/0000-0001-6165-2879
Jian-Ping Zou http://orcid.org/0000-0003-4151-4633
Jian-Ping Xiong http://orcid.org/0000-0003-0398-6090
Xiao-Jun Xiang http://orcid.org/0000-0002-8734-584X
Jun Deng http://orcid.org/0000-0002-7644-5853
Funding Agency and Grant Number
Corresponding Author Jun Deng, PhD, Assistant Professor, Department of Jiangxi Key Laboratory for Individualized Cancer Therapy, The First Affiliated Hospital of Nanchang University, No. 17 Yongwai Street, Nanchang 330006, Jiangxi Province, China. dengjun19871106@ncu.edu.cn
Key Words Ubiquitin-specific protease 15; Gastric cancer; Wnt/β-catenin; Cell proliferation; Cell invasion; Epithelial–mesenchymal transition
Core Tip Ubiquitin-specific protease 15 (USP15) was up-regulated in gastric cancer (GC) cells and tissues, and was associated with poor prognosis in patients with GC. USP15 promoted cell proliferation, invasion and epithelial–mesenchymal transition of GC cells in vitro and tumor growth in vivo. Mechanistic studies showed that USP15 functioned as a tumor promoter in GC by regulating Wnt/β-catenin signaling pathway. USP15 is expected to be a novel potential target for GC therapy.
Publish Date 2021-07-12 00:42
Citation Zhong M, Zhou L, Fang Z, Yao YY, Zou JP, Xiong JP, Xiang XJ, Deng J. Ubiquitin-specific protease 15 contributes to gastric cancer progression via regulating the Wnt/β-catenin signaling pathway. World J Gastroenterol 2021; 27(26): 4221-4235
URL https://www.wjgnet.com/1007-9327/full/v27/i26/4221.htm
DOI https://dx.doi.org/10.3748/wjg.v27.i26.4221
Full Article (PDF) WJG-27-4221.pdf
Full Article (Word) WJG-27-4221.docx
The ARRIVE Guidelines 65488-The-ARRIVE-Guidelines-revision.pdf
Manuscript File 65488-Review-FilipodiaCL.docx
Answering Reviewers 65488-Answering reviewers.pdf
Audio Core Tip 65488-Audio core tip.mp3
Biostatistics Review Certificate 65488-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 65488-Conflict-of-interest statement.pdf
Copyright License Agreement 65488-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 65488-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 65488-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 65488-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 65488-Language certificate.pdf
Peer-review Report 65488-Peer-review(s).pdf
Scientific Misconduct Check 65488-Scientific misconduct check.pdf
Scientific Editor Work List 65488-Scientific editor work list.pdf