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8/4/2021 7:56:20 AM | Browse: 394 | Download: 675
Publication Name World Journal of Gastroenterology
Manuscript ID 65531
Country/Territory Japan
Received
2021-03-09 12:38
Peer-Review Started
2021-03-09 12:43
To Make the First Decision
Return for Revision
2021-04-17 13:21
Revised
2021-04-30 14:38
Second Decision
2021-07-15 03:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-07-15 07:45
Articles in Press
2021-07-15 07:45
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-07-30 08:06
Publish the Manuscript Online
2021-08-04 07:56
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Engineering, Biomedical
Manuscript Type Review
Article Title Hepatitis B virus infection modeling using multi-cellular organoids derived from human induced pluripotent stem cells
Manuscript Source Invited Manuscript
All Author List Di Cao, Jian-Yun Ge, Yun Wang, Tatsuya Oda and Yun-Wen Zheng
ORCID
Author(s) ORCID Number
Di Cao http://orcid.org/0000-0002-9711-5001
Jian-Yun Ge http://orcid.org/0000-0002-4890-0628
Yun Wang http://orcid.org/0000-0002-9281-0048
Tatsuya Oda http://orcid.org/0000-0001-6115-0158
Yun-Wen Zheng http://orcid.org/0000-0001-9002-3190
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 82070638
National Natural Science Foundation of China 81770621
JSPS KAKENHI JP18H02866
Corresponding Author Yun-Wen Zheng, PhD, Associate Professor, Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Faculty of Medicine, University of Tsukuba, Tennodai 1-1-1, Tsukuba 305-8575, Ibaraki, Japan. ywzheng@md.tsukuba.ac.jp
Key Words Hepatitis B virus; Induced pluripotent stem cells; Liver organoid; Multi-cellular organoid; Modeling; Transplantable
Core Tip The development of an effective treatment for hepatitis B virus relies on reliable and reproducible in vitro modeling systems. Recently, three-dimensional multi-cellular organoid systems have attracted considerable attention owing to their superior susceptibility and capability to precisely recapitulate the virus life cycle. Recent advances in organoid-generating strategies, particularly those derived from human induced pluripotent stem cells, together with future improvements in genetic modification and scalability, will undoubtedly promote personalized disease modeling and drug development.
Publish Date 2021-08-04 07:56
Citation Cao D, Ge JY, Wang Y, Oda T, Zheng YW. Hepatitis B virus infection modeling using multi-cellular organoids derived from human induced pluripotent stem cells. World J Gastroenterol 2021; 27(29): 4784-4801
URL https://www.wjgnet.com/1007-9327/full/v27/i29/4784.htm
DOI https://dx.doi.org/10.3748/wjg.v27.i29.4784
Full Article (PDF) WJG-27-4784.pdf
Full Article (Word) WJG-27-4784.docx
Manuscript File 65531_Auto_Edited-JPY.docx
Answering Reviewers 65531-Answering reviewers.pdf
Audio Core Tip 65531-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 65531-Conflict-of-interest statement.pdf
Copyright License Agreement 65531-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 65531-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 65531-Language certificate.pdf
Peer-review Report 65531-Peer-review(s).pdf
Scientific Misconduct Check 65531-Scientific misconduct check.pdf
Scientific Editor Work List 65531-Scientific editor work list.pdf