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Articles Published Processes
7/23/2021 8:10:13 AM | Browse: 329 | Download: 591
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Received |
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2021-03-11 14:34 |
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Peer-Review Started |
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2021-03-11 14:40 |
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To Make the First Decision |
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Return for Revision |
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2021-03-29 14:39 |
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Revised |
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2021-04-14 15:14 |
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Second Decision |
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2021-05-25 14:53 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-05-25 15:22 |
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Articles in Press |
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2021-05-25 15:22 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-06-28 06:17 |
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Typeset the Manuscript |
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2021-07-11 08:19 |
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Publish the Manuscript Online |
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2021-07-23 08:10 |
ISSN |
1948-5182 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Review |
Article Title |
Liver injury associated with drug intake during pregnancy
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Manuscript Source |
Invited Manuscript |
All Author List |
Priyanka Kamath, Ashwin Kamath and Sheetal D Ullal |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Ashwin Kamath, MD, Associate Professor, Deputy Director, Department of Pharmacology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Light House Hill Road, Manipal 575001, Karnataka, India. ashwin.kamath@manipal.edu |
Key Words |
Drug induced liver injury; Pregnant women; Liver failure; Adverse effects; Pregnancy outcome; Registries |
Core Tip |
Drug-induced liver injury is a rare but potentially life-threatening consequence of drug administration. Few drugs are indicated for use in pregnant women based on their lack of teratogenic risk; however, these can be hepatotoxic. This review collates information from case reports and other research studies to present the current knowledge regarding the hepatotoxic potential of drugs used in pregnancy. The challenges in diagnosis and methods for causality assessment are described. Attempts to generate evidence by formulating guidelines enabling the conduct of inclusive clinical trials involving women as well as reinforcing the pharmacovigilance activities by developing adverse event registries are described. |
Publish Date |
2021-07-23 08:10 |
Citation |
Kamath P, Kamath A, Ullal SD. Liver injury associated with drug intake during pregnancy. World J Hepatol 2021; 13(7): 747-762 |
URL |
https://www.wjgnet.com/1948-5182/full/v13/i7/747.htm |
DOI |
https://dx.doi.org/10.4254/wjh.v13.i7.747 |
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