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2/22/2022 9:25:37 AM | Browse: 374 | Download: 660
Publication Name World Journal of Hepatology
Manuscript ID 65916
Country/Territory Argentina
Received
2021-03-18 01:39
Peer-Review Started
2021-03-18 02:14
To Make the First Decision
Return for Revision
2021-07-18 05:06
Revised
2021-08-22 15:06
Second Decision
2022-01-24 03:56
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-01-25 03:26
Articles in Press
2022-01-25 03:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-02-15 09:28
Publish the Manuscript Online
2022-02-22 09:25
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Hepatocellular carcinoma in patients with metabolic dysfunction-associated fatty liver disease: Can we stratify at-risk populations?
Manuscript Source Invited Manuscript
All Author List Eduardo Fassio, Fernando J Barreyro, M Soledad Pérez, Diana Dávila, Graciela Landeira, Gisela Gualano and Gabriela Ruffillo
ORCID
Author(s) ORCID Number
Eduardo Fassio http://orcid.org/0000-0002-9092-464X
Fernando J Barreyro http://orcid.org/0000-0002-0410-2982
M Soledad Pérez http://orcid.org/0000-0002-1976-1614
Diana Dávila http://orcid.org/0000-0001-5906-1535
Graciela Landeira http://orcid.org/0000-0003-0015-1397
Gisela Gualano http://orcid.org/0000-0002-8580-9284
Gabriela Ruffillo http://orcid.org/0000-0001-5266-8609
Funding Agency and Grant Number
Corresponding Author Eduardo Fassio, MD, Hepatology Section, Gastroenterology Service, Hospital Nacional Prof. Alejandro Posadas, Av. Presidente Illia y Marconi, s/n, El Palomar 1684, Buenos Aires, Argentina. efassio@intramed.net
Key Words Hepatocellular carcinoma; Metabolic dysfunction-associated fatty liver disease; Nonalcoholic fatty liver disease; Surveillance for hepatocellular carcinoma; Incidence of hepatocellular carcinoma; Nonalcoholic steatohepatitis
Core Tip Metabolic dysfunction-associated fatty liver disease (MAFLD) affects 25% of general population worldwide. Within that huge number of patients, a minority will progress to cirrhosis, with an annual incidence rate of hepatocellular carcinoma (HCC) > 1%. In them, surveillance for HCC by means of ultrasound with or without alpha-fetoprotein measurement is cost-effective. In patients with MAFLD cirrhosis who are men, older and diabetic, risk is even higher and magnetic resonance imaging might be a better screening test. However, the great challenge is stratifying the HCC risk in patients with MAFLD without cirrhosis. Factors that can help to stratify their risk (genetic, demographic, metabolic, non-invasive fibrosis tests) will be reviewed.
Publish Date 2022-02-22 09:25
Citation Fassio E, Barreyro FJ, Pérez MS, Dávila D, Landeira G, Gualano G, Ruffillo G. Hepatocellular carcinoma in patients with metabolic dysfunction-associated fatty liver disease: Can we stratify at-risk populations? World J Hepatol 2022; 14(2): 354-371
URL https://www.wjgnet.com/1948-5182/full/v14/i2/354.htm
DOI https://dx.doi.org/10.4254/wjh.v14.i2.354
Full Article (PDF) WJH-14-354.pdf
Full Article (Word) WJH-14-354.docx
Manuscript File 65916_Auto_Edited.docx
Answering Reviewers 65916-Answering reviewers.pdf
Audio Core Tip 65916-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 65916-Conflict-of-interest statement.pdf
Copyright License Agreement 65916-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 65916-Language certificate.pdf
Peer-review Report 65916-Peer-review(s).pdf
Scientific Misconduct Check 65916-Bing-Wang JL-1.jpg
Scientific Misconduct Check 65916-Bing-Fan JR-2.png
Scientific Editor Work List 65916-Scientific editor work list.pdf