| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Autobiography |
| Article Title |
Serum and urine metabolomic fingerprinting in diagnostics of inflammatory bowel diseases
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Tomasz Dawiskiba, Stanisław Deja, Agata Mulak, Adam Ząbek, Ewa Jawień, Dorota Pawełka, Mirosław Banasik, Agnieszka Mastalerz-Migas, Waldemar Balcerzak, Krzysztof Kaliszewski, Jan Skóra, Piotr Barć, Krzysztof Korta, Kornel Pormańczuk, Przemyslaw Szyber, Adam Litarski and Piotr Młynarz |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Wroclaw Medical University Research Program |
15/Pbmn |
|
| Corresponding Author |
Tomasz Dawiskiba, MD, PhD, Department of Vascular, General and Transplantation Surgery, Wroclaw Medical University, 213 Borowska Street, 50-556 Wroclaw, Poland. tomasz.dawiskiba@umed.wroc.pl |
| Key Words |
Metabolomics; Inflammatory bowel disease; Ulcerative colitis; Crohn's disease; Proton nuclear magnetic resonance spectroscopy; Urine; Serum; Partial least-squares-discriminant analysis |
| Core Tip |
This study demonstrates that proton nuclear magnetic resonance -based metabolic fingerprinting of human serum and urine combined with multivariate data analysis could be a useful tool for differentiation between the active and remission phase of the disease that is of great importance in inflammatory bowel diseases (IBD) monitoring. At the same time, the results indicate that this diagnostic method has rather a weak potential in the differential diagnosis of IBD. |
| Publish Date |
2014-01-20 17:10 |
| Citation |
Dawiskiba T, Deja S, Mulak A, Z?bek A, Jawień E, Pawelka D, Banasik M, Mastalerz-Migas A, Balcerzak W, Kaliszewski K, Skóra J, Barc P, Korta K, Pormańczuk K, Szyber P, Litarski A, Mlynarz P. Serum and urine metabolomic fingerprinting in diagnostics of inflammatory bowel diseases. World J Gastroenterol 2014; 20(1): 163-174 |
| URL |
http://www.wjgnet.com/1007-9327/full/v20/i1/163.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v20.i1.163 |
