Publication Name	World Journal of Gastroenterology
Manuscript ID	6628
Country	Malaysia

Received	2013-10-26 08:47
Peer-Review Started	2013-10-26 12:28
To Make the First Decision	2014-01-09 13:29
Return for Revision	2014-01-10 12:07
Revised
Second Decision	2014-05-05 08:42
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-05-05 09:48
Articles in Press	2014-05-23 10:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-08-19 15:00
Publish the Manuscript Online	2014-09-07 13:31

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Biotechnology & Applied Microbiology
Manuscript Type	Topic Highlights
Article Title	Phage display creates innovative applications to combat hepatitis B virus
Manuscript Source	Invited Manuscript
All Author List	Wen Siang Tan and Kok Lian Ho
Funding Agency and Grant Number
Corresponding Author	Wen Siang Tan, PhD, Department of Microbiology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia. wstan@upm.edu.my
Key Words	Phage display; Hepatitis B virus; Epitope mapping; Drug delivery; Gene delivery; Antiviral drug; Therapeutics; Diagnosis; Hepatocellular carcinoma; Virus-like particle; Vaccine
Core Tip	Hepatitis B virus (HBV) poses a major health problem worldwide and currently there is no effective treatment for HBV infection. Treatments of patients with nucleoside analogues have resulted in the selection of vaccine escape and drug resistant mutants. Most frightening, HBV is now linking arms with human immunodeficiency virus to threaten the world. Phage display has been employed extensively to solve these life-threatening problems. This article reviews critically the innovative applications of phage display in epitope mapping and the development of vaccines, therapeutic agents, diagnostic reagents, as well as gene and drug delivery systems.
Publish Date	2014-09-07 13:31
Citation	Tan WS, Ho KL. Phage display creates innovative applications to combat hepatitis B virus. World J Gastroenterol 2014; 20(33): 11650-11670
URL	http://www.wjgnet.com/1007-9327/full/v20/i33/11650.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i33.11650

Full Article (PDF)	WJG-20-11650.pdf
Full Article (Word)	WJG-20-11650.doc
Manuscript File	6628-Review.docx
Answering Reviewers	6628-Answering reviewers.pdf
Copyright License Agreement	6628-Copyright assignment.pdf
Peer-review Report	6628-Peer review(s).pdf
Scientific Editor Work List	6628-Scientific editor work list.pdf