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1/20/2022 10:47:59 AM | Browse: 84 | Download: 113
Publication Name World Journal of Stem Cells
Manuscript ID 66280
Country/Territory Spain
Received
2021-03-24 16:45
Peer-Review Started
2021-03-24 16:47
To Make the First Decision
Return for Revision
2021-06-05 01:43
Revised
2021-06-21 20:56
Second Decision
2021-12-31 03:40
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-12-31 22:31
Articles in Press
2021-12-31 22:31
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-01-06 08:29
Publish the Manuscript Online
2022-01-20 10:47
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Systematic Reviews
Article Title Stem cell therapy applied for digestive anastomosis: Current state and future perspectives
Manuscript Source Invited Manuscript
All Author List Jacobo Trébol, Tihomir Georgiev-Hristov, Isabel Pascual-Miguelañez, Hector Guadalajara, Mariano García-Arranz and Damian García-Olmo
ORCID
Author(s) ORCID Number
Jacobo Trébol http://orcid.org/0000-0002-6579-533X
Tihomir Georgiev-Hristov http://orcid.org/0000-0002-4428-6413
Isabel Pascual-Miguelañez http://orcid.org/0000-0003-2088-9030
Hector Guadalajara http://orcid.org/0000-0001-6297-9347
Mariano García-Arranz http://orcid.org/0000-0002-6266-9055
Damian García-Olmo http://orcid.org/0000-0002-9369-2338
Funding Agency and Grant Number
Corresponding Author Jacobo Trébol, MD, PhD, Adjunct Professor, Surgeon, Surgical Oncologist, Servicio de Cirugía General y del Aparato Digestivo, Complejo Asistencial Universitario de Salamanca, Paseo de San Vicente, No. 58-182, Salamanca 37007, Spain. jtrebol@saludcastillayleon.es
Key Words Surgical anastomosis; Anastomotic leak; Digestive system surgical procedure; Cell transplantation; Cell therapy; Stem cells; Tissue engineering
Core Tip Digestive anastomoses leakages reflect impaired healing, are frequent and are associated with severe consequences. Despite technical and technological advancements, leakage rates have remained stable in the last decades. Stem cells (SCs) could improve anastomotic healing, as they have in other altered healing conditions. We present a descriptive review of the published literature about digestive anastomoses and sutures and SCs, analyzing the results and discussing their limitations and concerns. Eighteen preclinical studies have confirmed the feasibility and safety and have shown interesting results, however, with some limitations and high heterogenicity. Additional studies and better models are needed prior to human testing.
Publish Date 2022-01-20 10:47
Citation Trébol J, Georgiev-Hristov T, Pascual-Miguelañez I, Guadalajara H, García-Arranz M, García-Olmo D. Stem cell therapy applied for digestive anastomosis: Current state and future perspectives. World J Stem Cells 2022; 14(1): 117-141
URL https://www.wjgnet.com/1948-0210/full/v14/i1/117.htm
DOI https://dx.doi.org/10.4252/wjsc.v14.i1.117
Full Article (PDF) WJSC-14-117.pdf
Full Article (Word) WJSC-14-117.docx
Manuscript File 66280_Auto_Edited.docx
Answering Reviewers 66280-Answering reviewers.pdf
Audio Core Tip 66280-Audio core tip.wav
Conflict-of-Interest Disclosure Form 66280-Conflict-of-interest statement.pdf
Copyright License Agreement 66280-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 66280-Language certificate.pdf
Peer-review Report 66280-Peer-review(s).pdf
Scientific Editor Work List 66280-Scientific editor work list.pdf