| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Serum soluble suppression of tumorigenicity 2 as a novel inflammatory marker predict the severity of acute pancreatitis
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yan Zhang, Bo Cheng, Zhong-Wei Wu, Zong-Chao Cui, Yao-Dong Song, San-Yang Chen, Yan-Na Liu and Chang-Ju Zhu |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Henan Province Education Department for Henan Province University Key Scientific Research Project |
20A320018 |
| Henan Province Education Department for Henan Province University Key Scientific Research Project |
20A320064 |
|
| Corresponding Author |
Chang-Ju Zhu, PhD, Chief Doctor, Chief Physician, Director, Doctor, Professor, Department of Emergency, the First Affiliated Hospital of Zhengzhou University, No. 1 Eastern Jianshe Road, Zhengzhou 450052, Henan Province, China. zhuchangju98@163.com |
| Key Words |
Acute pancreatitis; Soluble suppression of tumorigenicity 2; T-helper 1 cells; T-helper 2 cells; Interleukin-33; Biomarker |
| Core Tip |
Acute pancreatitis (AP) is an inflammatory disease in which the regulatory pathway is complex and not well understood. The interleukin (IL)-33/ST2L functional pathway is involved in the pathological process of AP. Suppression of tumorigenicity 2 protein (ST2) is a soluble receptor, which is released in the circulation acts as a decoy receptor by binding IL-33. However, soluble ST2 (sST2), as one of the most promising disease biomarker, has not been studied in the development of AP. In this study we studied the role of sST2 as an inflammatory marker for predicting the severity of acute pancreatitis. |
| Publish Date |
2021-10-12 06:53 |
| Citation |
Zhang Y, Cheng B, Wu ZW, Cui ZC, Song YD, Chen SY, Liu YN, Zhu CJ. Serum soluble suppression of tumorigenicity 2 as a novel inflammatory marker predict the severity of acute pancreatitis. World J Gastroenterol 2021; 27(38): 6489-6500 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i38/6489.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i38.6489 |
