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9/15/2021 10:33:58 AM | Browse: 335 | Download: 737
Publication Name World Journal of Gastroenterology
Manuscript ID 67143
Country Hungary
Received
2021-04-30 07:39
Peer-Review Started
2021-04-30 07:41
To Make the First Decision
Return for Revision
2021-06-23 01:45
Revised
2021-07-07 16:27
Second Decision
2021-08-24 03:27
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-08-25 08:15
Articles in Press
2021-08-25 08:15
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-09-10 14:23
Publish the Manuscript Online
2021-09-15 10:33
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type Retrospective Study
Article Title Diagnosis of focal liver lesions with deep learning-based multi-channel analysis of hepatocyte-specific contrast-enhanced magnetic resonance imaging
Manuscript Source Invited Manuscript
All Author List Róbert Stollmayer, Bettina K Budai, Ambrus Tóth, Ildikó Kalina, Erika Hartmann, Péter Szoldán, Viktor Bérczi, Pál Maurovich-Horvat and Pál N Kaposi
ORCID
Author(s) ORCID Number
Róbert Stollmayer http://orcid.org/0000-0003-4673-7588
Bettina K Budai http://orcid.org/0000-0002-3982-7887
Ambrus Tóth http://orcid.org/0000-0002-1150-957X
Ildikó Kalina http://orcid.org/0000-0002-2647-9123
Erika Hartmann http://orcid.org/0000-0001-6073-9286
Péter Szoldán http://orcid.org/0000-0002-3808-8541
Viktor Bérczi http://orcid.org/0000-0003-4386-2527
Pál Maurovich-Horvat http://orcid.org/0000-0003-0885-736X
Pál N Kaposi http://orcid.org/0000-0002-7150-3495
Funding Agency and Grant Number
Corresponding Author Bettina K Budai, MD, N/A, Department of Radiology, Medical Imaging Centre, Faculty of Medicine, Semmelweis University, Korányi Sándor st. 2., Budapest 1083, Hungary. budai.bettina@med.semmelweis-univ.hu
Key Words Artificial intelligence; Multi-parametric magnetic resonance imaging; Hepatocyte-specific contrast; Densely connected convolutional network; Hepatocellular carcinoma; Focal nodular hyperplasia
Core Tip Our study aimed to assess the performance of two-dimensional (2D) and three-dimensional (3D) densely connected convolutional neural networks (DenseNets) in the classification of focal liver lesions (FLLs) based on multi-parametric magnetic resonance imaging (MRI) with hepatocyte-specific contrast. We used multi-channel data input to train our networks and found that both 2D and 3D-DenseNets can differentiate between focal nodular hyperplasias, hepatocellular carcinomas or liver metastases with excellent accuracy. We conclude that DensNets can reliably classify FLLs based on multi-parametric and hepatocyte-specific post-contrast MRI. Meanwhile, multi-channel input is advantageous when the number of clinical cases available for model training is limited.
Publish Date 2021-09-15 10:33
Citation Stollmayer R, Budai BK, Tóth A, Kalina I, Hartmann E, Szoldán P, Bérczi V, Maurovich-Horvat P, Kaposi PN. Diagnosis of focal liver lesions with deep learning-based multi-channel analysis of hepatocyte-specific contrast-enhanced magnetic resonance imaging. World J Gastroenterol 2021; 27(35): 5978-5988
URL https://www.wjgnet.com/1007-9327/full/v27/i35/5978.htm
DOI https://dx.doi.org/10.3748/wjg.v27.i35.5978
Full Article (PDF) WJG-27-5978.pdf
Full Article (Word) WJG-27-5978.docx
Manuscript File 67143_Auto_Edited-JPY.docx
Answering Reviewers 67143-Answering reviewers.pdf
Audio Core Tip 67143-Audio core tip.mp3
Biostatistics Review Certificate 67143-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 67143-Conflict-of-interest statement.pdf
Copyright License Agreement 67143-Copyright license agreement.PDF
Signed Informed Consent Form(s) or Document(s) 67143-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 67143-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 67143-Language certificate.pdf
Peer-review Report 67143-Peer-review(s).pdf
Scientific Misconduct Check 67143-Bing-Fan JR-2.png
Scientific Misconduct Check 67143-Scientific misconduct check.pdf
Scientific Editor Work List 67143-Scientific editor work list.pdf